抗菌药物临床应用专项整治对腹股沟疝围手术期预防用药的影响  

Effect of special rectification for clinical antibiotics application on antibiotics prophylaxis during perioperative period of inguinal hernia surgery

作　　者：殷卫清[1] 沈宏[1] 归莱[1] 唐叶秋[1] 

机构地区：[1]常熟市第一人民医院临床药学室,江苏常熟215500

出　　处：《中华医院感染学杂志》2012年第18期4112-4114,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解抗菌药物临床应用专项整治活动对普外科围手术期抗菌药物应用的影响。方法采取回顾性调查方法,随机抽取2010年7-8月62例(对照组)和2011年7-8月72例(干预组)行腹股沟疝手术的患者出院病历,填写抗菌药物应用情况调查表,并进行比较分析。结果干预前后抗菌药物使用率显著降低,分别为100.00%、58.33%(P<0.05),预防用药指征符合率从45.16%提高至85.71%(P<0.05);首剂给药时机合理率分别为4.84%、28.57%(P<0.05);平均用药时间分别为(4.72±1.50)d、(2.06±1.47)d(P<0.001),差异均有统计学意义;给药途径均以静脉滴注且无抗菌药物联合应用现象。结论抗菌药物临床应用的专项整治,使医院腹股沟疝围手术抗菌药物应用的合理性显著提高,但仍有不足之处需要多方面共同管理和改进。OBJECTIVE To investigate the effect of the special rectification for clinical antibiotics application on the use of antibiotics in general surgery department during perioperative period. METHODS The medical records of the discharge patients undergoing inguinal hernia surgery were randomly extracted from Jul to Aug 2010 （the control group） and from Jul to Aug 2011 （the intervention group）. By means of self-designed questionnaires, the application of antibiotics was taken for statistical analysis. RESULTS The utilization rates of antibiotics were significantly decreased before and after the interventions, which were 100.00% and 58. 33%, respectively （P（ 0.05）, the coincidence rate of the antibiotics medication indications raised from 45.16% to 85.71% （P（0.05） ; the reasonable rates of the first medication were 4. 84% and 28, 57%, respectively （P〈0. 05）; the median medication duration were （4. 72± 1. 50） days and （2. 06± 1. 47） days （P〈0. 001）,the differences were statistically significant; both groups were administrated with antibiotics by the intravenous infusion, and there were no combination use of antibiotics. CONCLUSION The special rectification for clinical antibiotics application can significantly improve the rationality of use of antibiotics during preoperative period of inguinal hernia surgery yet remains with the insufficiencies to be further improved.

关 键 词：腹股沟疝 围手术期 抗菌药物 专项整治 干预 

分 类 号：R978.1[医药卫生—药品]