手足口病再感染的地理流行病学特征分析  

Analysis for the Geographic epidemiological characteristics of reinfected cases of hand-foot-mouth

作　　者：王彦霞 茹维平 康锴 潘静静 陈豪敏 许汴利 

机构地区：[1]河南省郑州疾病预防控制中心传染病所,河南省郑州450016

出　　处：《国际病毒学杂志》2012年第4期167-172,共6页International Journal of Virology

基　　金：河南省医学科技攻关项目《手足口病流行规律、预防控制措施及其效果评价》（No.2011020177）

摘　　要：目的调查手足口病再感染率和病原分布情况，分析其地理流行病学特征。方法利用中国疾病预防控制信息系统中2008—2010年河南省手足口病个案资料，采用地理流行病学的方法，分析再感染率和病原的分布特征。结果河南省2008—2010年手足口病再感染率约为7．74％。；其分布集中在豫中部（郑州市、平顶山市、许昌市等）和豫北地区（鹤壁市、焦作市等）；手足口病发病率高的地区，再感染发生率亦高；在EV71流行期伴随着CoxA16或其他肠道病毒同时流行的地区再感染率较高。结论手足口病再感染存在地域差异，病原在不同地区存在变化，手足LI病流行期间肠道病毒血清型种类多的地区再感染发生率高，提示手足口病的预防控制工作要因地制宜。Objective To investigate the reinfection rate and pathogen distribution, analyze geo- graphic epidemiological characteristics of hand-foot-mouth disease （HFMD）. Methods The data of HFMD cases in Henan during 2008-2010 were collected from China Infornlation System for Diseases Control and Prevention and was analyzed by descriptive epidemiological methods and the thematic map of the disease dis- tribution was created with GIS software. Results The reinfection rate of HFMD was 7.74%0 during 2008 and 2010 in Henan. The thematic map showed that most of the reinfection HFMD occurred in the central re- gion of Henan, especially in Zhengzhou , Pingdingshan, Xuchang et al. And in the northern area of Hennan, especially in Hebi, Jiaozuo et al. There were higher reinfection rates, in the area of EV71 epidemic along with CoxA16 or other enteroviruses. Conclusion There was regional difference of HFMD reinfection and pathogen distribution. The prevention and control of reinfection should be strengthened especially in the regions of HFMD epidemic with many kinds of enterovirus serotypes.

关 键 词：手足口病 再感染 地理流行病学 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]