注入前向运动精子数对丈夫精液宫腔内人工授精妊娠结局的影响  

The influence of processed total motile sperm count on pregnancy rate of husband sperm intrauterine insemination

作　　者：范雪梅[1] 杨丹[1] 漆著[1] 杜娟[1] 

机构地区：[1]成都中医药大学第二附属医院生殖中心,四川成都610041

出　　处：《实用医院临床杂志》2012年第5期72-73,共2页Practical Journal of Clinical Medicine

摘　　要：目的探讨注入前向运动精子数对丈夫精液宫腔内人工授精(IUI)临床妊娠结局的影响。方法 2007年1月至2011年12月在我院生殖中心接受IUI的不孕症夫妇137对,共216个周期,按宫腔内注入的前向运动精子数(Processed to-tal motile sperm count,PTMS)分为4组:A组≤3×106,B组(3～10)×106,C组(10～20)×106,D组>20×106,比较各组临床妊娠率。结果本组资料IUI总的妊娠率为10.19%,A组临床妊娠率低于B组和C组,但组间比较差异均无统计学意义(P>0.05)。结论宫腔内注入PTMS在(3～20)×106范围内可获得理想的临床妊娠率,适宜进行宫腔内人工授精。PTMS≤3×106时,建议行体外授精/卵胞浆内单精子注射-胚胎移植(IVF/ICSI-ET)。Objective To analyze the influence of processed total motile sperm（PTMS） count of husband on clinical pregnancy rate of intrauterine insemination（IUI）. Methods A total of 216 cycles of IUI was involved in the study. The cycles were divided into 4 groups according to the PTMS count：Group A ≤ 3×106,Group B = （3-10） ×10^6 ,Group C = （ 10 - 20） ×10^6 and Group D〉20×10^6. The clinical pregnancy rates among different groups were compared. Results The average pregnancy rate of IUI was 10.19%. The low-est clinical pregnancy rate was found in group A while the highest clinical pregnancy rate was found in the group B and C. Conclusions Ideal pregnancy rate can be achieved when the PTMS count is between 3×10^6and 20x106 ,that may be feasible to do IUI. The patients may be suggested to do IVF/ICSI-ET if their PTMS count was ≤3×10^6.

关 键 词：前向运动精子数 人工授精 妊娠率 

分 类 号：R711.6[医药卫生—妇产科学] R714.12[医药卫生—临床医学]