前列地尔在治疗不稳定性心绞痛患者中的应用效果研究  

Investigation of the efficacy of Alprostadil for patients with unstable angina

作　　者：游波[1] 

机构地区：[1]四川省成都市第六人民医院心内科,四川成都610051

出　　处：《中国医药导报》2012年第25期94-95,共2页China Medical Herald

摘　　要：目的探讨前列地尔在不稳定性心绞痛患者中的应用疗效。方法选择2011年1月～2012年1月在我院心内科住院治疗的100例不稳定性心绞痛患者为研究对象,应用随机数字表法分为对照组和观察组,每组各50例。对照组患者采用卧床休息、低盐饮食、低流量吸氧等常规治疗,而观察组患者则在上述治疗的基础上加用前列地尔对其进行治疗,比较2周后对照组和观察组患者的临床治疗效果、心电图改善情况及药物不良反应发生情况。结果经过2周的治疗,观察组患者临床症状疗效(88.00%)明显优于对照组(70.00%)(P<0.05);观察组患者心电图改善疗效(90.00%)明显优于对照组(76.00%)(P<0.05)。结论前列地尔治疗不稳定性心绞痛临床疗效确切,安全性高,不良反应少,值得临床推广应用。Objective To investigate the efficacy of Alprostadil for patients with unstable angina. Methods 100 cases of patients with unstable angina were collected in the department of cardiology in our hospital from January 2011 to January 2012 and divided into control group and observation group equally by using a random number table, patients in the control group were given conventional treatment of bed rest, low-sah diet, low-flow oxygen, patients in the observation group were given Alprostadil on the base of the above treatment. The clinical efficacy, the efficacy of ECG, drug adverse reaction of each group were evaluated after two weeks. Results The total efficient rate was higher in the observation group than that in the control group （88.00% vs 70.00%, P 〈 0.05）, the efficacy of ECG was higher in the observation group than that in the control group （90.00% vs 76.00%, P 〈 0.05）. Conclusion The efficacy of Alprostadil for patients with unstable angina is safe and reliable, it is worthy of clinical application.

关 键 词：前列地尔 不稳定性心绞痛 临床疗效 

分 类 号：R541.4[医药卫生—心血管疾病]