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作 者:陈庭佳[1] 彭玉峰[1] 戴洁红[1] 何源峰[1] 卓柳亭[1] 王新凤[1]
机构地区:[1]中山大学附属第一医院东校区门诊部,广东广州510006
出 处:《中国当代医药》2012年第25期87-88,共2页China Modern Medicine
摘 要:目的探讨上呼吸道感染后咳嗽的治疗方案。方法将80例上呼吸道感染后咳嗽的患者随机分成两组,A组40例,给予口服复方甲氧那明(阿斯美)联合酮替芬治疗;B组40例,给予口服左氧氟沙星胶囊(悉复欢)联合复方甘草合剂治疗。治疗时间均为10d。结果治疗后A组总有效率为92.5%,B组总有效率为37.5%,两组比较,差异有统计学意义(P<0.01)。A组病程(7.56±3.21)d,较B组的(11.78±4.12)d明显缩短,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论复方甲氧那明(阿斯美)联合酮替芬对上呼吸道感染后咳嗽疗效较好,而且不良反应较轻,安全性较好,值得在高校门诊部中推广应用。Objective To explore the treatment of cough following acute upper respiratory tract infections. Methods A total of 8 patients with cough subsequent to acute upper respiratory tract infections were assigned to group A and group B at random. The 40 cases in group A were treated with compound methoxyphenamine capsules (ASMETON) combined with ketotifen, while the 40 eases in group B received levofloxacin capsules (eiprofloxacin) combined with Fufang Gancao Heji, both for 10 days. Results The total effective rate of relieving cough was 92.5% in group A, 37.5% in group B. Group A showed significant differences in clinical efficacy compared with group B (P 〈 0.01). Cough duration of patients in group A was (7.56±3.21) days, (11.78±4.12) days in group B. Group A showed significant differences in cough duration compared with group B (P 〈 0.05). The incidence rates of adverse reactions were not statistically different between the two groups (P 〉 0.05). Conclusion Compound methoxyphenamine combined with Ketotifen displays better effects, minor adverse reactions, and better safety in the treatment of cough following acute upper respiratory tract infection, it can be widely used in uni- versity clinic.
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