三色马先蒿、决明子、连翘抗运动性疲劳的活性研究  

ANTI-SPORT FATIGUE EFFECTS OF PEDICULARIS TRICOLOR, SEMEN CASSIA, FORSYTHIA SUSPENSA

作　　者：朱梅菊[1] 谭宁华[2] 朱洪竹[1] 熊静宇[3] 罗齐军[3] 刘紫荆[3] 

机构地区：[1]井冈山大学体育学院,江西吉安510006 [2]中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南昆明650204 [3]湛江师范学院体育科学学院,广东湛江524048

出　　处：《井冈山大学学报（自然科学版）》2012年第5期71-74,共4页Journal of Jinggangshan University (Natural Science)

基　　金：国家自然科学基金项目(31160217);广东省自然科学基金项目(10152404801000008)

摘　　要：目的研究三色马先蒿、决明子和连翘的抗运动性疲劳作用。方法以小鼠游泳训练为模型,观察上述三味中药对4周递增大强度负荷运动小鼠体重、食欲等疲劳相关症状和体征及力竭游泳时间的影响。结果实验第四周末单纯运动组小鼠活动减少,毛发枯萎,无光泽,有的小鼠出现大片脱毛现象,食欲减少,体重降低;而运动+决明子组、运动+连翘组和运动+三色马先蒿组上述疲劳相关的症状与体症明显减轻,食欲增加,体重持续增长。单纯运动组小鼠力竭游泳时间明显低其余三组,P<0.01。运动+三色马先蒿组小鼠力竭游泳时间明显高于运动+决明子组和运动+连翘组小鼠,P<0.05;与阳性对照组(人参提取物)比较,差异无显著性,P>0.05。结论三色马先蒿、决明子和连翘均具有一定的抗运动性疲劳作用,但以三色马先蒿的效果最好。Objective： To study the anti-sport fatigue Pedicularis tricolor, Semen cassia, Forsythia suspensa. effects of three traditional Chinese medicines （TCMs）, Methods： Using the model of mice swimming training to observe the effects of these three TCMs on mice body weight, appetite, other signs and symptoms-related fatigue, and the exhaustive swimming time by high-intensity swimming for four weeks. Results： Mice in exercised group showed reduced activities, withered hair, decreased appetite, and body weight lost after 4-week exercise, while mice administered with Pedicularis tricolor, Semen cassia, Forsythia suspensa showed these symptoms less significantly, i.e. increased appetite and body weight. The exhaustive swimming time involving mice administered with these plants, was longer than mice in exercised group after 4 weeks （P〈0.01）. The exhaustive swimming time in mice administered with Pedicularis tricolor was longer than that in mice administered with Semen cassia, Forsythia suspensa after 4 weeks （P〈0.05）. There was no significant difference in the exhaustive swimming time between mice administered with Pedicularis tricolor and Ginseng （regarded as the positive drug） （P 〉0.05）.Conclusion： Pedicularis tricolor, Semen cassia, Forsythia suspensa may possess anti-fatigue effects on exercised mice. Pedicularis tricolor was more active.

关 键 词：中药 疲劳 运动 

分 类 号：R337.2[医药卫生—人体生理学]