苏黄止咳胶囊治疗慢性阻塞性肺疾病咳嗽70例  

Randomized Controlled Study on Suhuang Zhike Capsules for Treatment of COPD Cough

作　　者：程莉[1] 刘茜[1] 

机构地区：[1]重庆市第三人民医院老年病科,重庆400014

出　　处：《中国药业》2012年第16期91-93,共3页China Pharmaceuticals

摘　　要：目的评估苏黄止咳胶囊短期治疗慢性阻塞性肺疾病(COPD)稳定期患者咳嗽的临床疗效和安全性。方法将140例COPD稳定期咳嗽患者随机均分为观察组和对照组,各70例。观察组口服苏黄止咳胶囊,对照组口服复方棕色合剂,两组均治疗21 d。对两组患者治疗前后的咳嗽症状进行评分,考察两组总有效率、停药1周后的复发率和不良反应情况。结果观察组总有效率为87.14%,对照组总有效率为68.57%,观察组明显优于对照组(P<0.05);观察组复发率为6.56%,对照组复发率为20.83%,观察组明显低于对照组(P<0.05);两组均无明显不良反应。结论苏黄止咳胶囊短期治疗COPD稳定期患者咳嗽安全、有效,停药后复发率低。Objective To evaluate the clinical effectiveness and safety of Suhuang Zhike Capsules in treating cough of chronic obstructive pulmonary disease（COPD）.Methods In the randomized controlled clinical study,140 cases of cough of COPD were divided into the treatment group（70 cases）treated by Suhuang Zhike Capsules,and the control group（70 cases）treated by Compound Brown Mixture,the treatment course was 21 d.The cough symptom was scored before and after treatment in the two groups.The effective rate,recurrence rate after 1 week of medication discontinuation and the adverse reactions were observed between the two groups.Results The effective rate was 87.14%in the treatment group and 68.57%in the control group,the treatment group was significantly superior to the control group（P 〈 0.05）.The recurrence rate after 1 week of medication discontinuation was 6.56%in the treatment group and 20.83%in the control group,the treatment group was significantly lower than the control group（P 〈 0.05）.No apparent adverse reactions occurred in both two groups.Conclusion Suhuang Zhike Capsules has an obvious effectiveness and safety in treating cough of COPD stable stage with the low recurrence rate after medication discontinuation.

关 键 词：慢性阻塞性肺疾病 咳嗽 苏黄止咳胶囊 疗效 

分 类 号：R285.6[医药卫生—中药学] R287[医药卫生—中医学]