复方α-酮酸对老年维持性血液透析患者营养状况的疗效观察  

Effects of α-ketoacid on Nutritional Status in Elderly Maintenance Hemodialysis Patients

作　　者：黄钱娥[1] 黄宇清[1] 郑林鸿[1] 陈汉威[1] 

机构地区：[1]中山大学附属博济医院(增城市人民医院)肾内科,广东广州511300

出　　处：《医学信息》2012年第7期134-135,共2页Journal of Medical Information

摘　　要：目的研究复方α-酮酸对改善老年维持性血液透析患者营养状况的有效性。方法选择60例老年维持性血液透析患者．随机分为治疗组30例和对照组30例，同时选择30例老年体检健康者为健康对照组。在常规血液透析基础上，治疗组口服开同（Ⅱ一酮酸）0．12g／（kg．d），对照组无治疗，总观察期6个月，分别在实验开始及6个月后检测患者血清白蛋白（ALB）、前白蛋白（PALB）、转铁蛋白（TF）、血红蛋白（Hb）、体重指数（BMI）、肱三头肌处皮褶厚度（TSF）。结果与健康者比较，治疗前维持性血液透析老年患者的ALB、PALB、TF、Hb、BMI、TSF显著降低（P〈0．05），6个月后治疗组与对照组相比，治疗组ALB、PALB、TF、Hb显著升高，差异有显著性P〈005。结论复方α-酮酸可改善维持性血液透析老年患者的营养状况。Objective： To investigate the Effects of α-ketoacid on nutritional status in elderly maintenance hemodialysis patients. Methods 60 elderly patients undergoing maintenance hemodialysis were randomly divided into therapy group （30 patients） and control group （30 patients）, 30 healthy elderly people as the normal control group,α-ketoacid was administered 0.12g/（kg.d） in therapy group for 6 months.The data of total albumin, pro- albumin, transferrin, hemoglobin,body mass index,triceps skinfold thickness before and after treatment were collected. Results Compared with the normal control group,the data of albumin, pro-albumin, transferrin, hemoglobin,body mass index,triceps skinfold thickness were significantly lower in the hemodalysis patients. Compared with the control group,the data of albumin, pro-albumin, transferrin, hemoglobin, were significantly higher in the therapy group after treatment. Conclusion The nutritional status of elderly maintenance hemodialysis patients could be improved byc α-Ketoacid treatment.

关 键 词：复方Α-酮酸 老年维持性血液透析患者 营养状况 

分 类 号：R459.5[医药卫生—治疗学]