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作 者:蔡鹰[1] 赵宁志[1] 张丽玲[1] 王爱萍[1]
出 处:《中国实验方剂学杂志》2012年第18期298-300,共3页Chinese Journal of Experimental Traditional Medical Formulae
基 金:中国博士后科学基金项目(20080441337)
摘 要:目的:观察回心草无糖颗粒治疗糖尿病合并冠心病心绞痛的临床疗效。方法:采用随机双盲对照方法,将105例糖尿病合并冠心病心绞痛病人分为两组:回心草无糖颗粒组(治疗组,15 g/包,2次/d,每次1包,冲服,66例)和麝香保心丸组(对照组,3次/d,每次2丸,口服,36例)。观察两组心绞痛发作频次、心电图、硝酸甘油停减率的变化。结果:心绞痛缓解总有效率:治疗组92.4%、对照组89.7%;心电图好转总有效率:治疗组57.6%、对照组43.6%(P<0.05);硝酸甘油停减率:治疗组83.3%、对照组79.5%。结论:回心草无糖颗粒对糖尿病合并冠心病心绞痛病人有效,疗效与麝香保心丸相当(心电图好转更明显)。Objective:To observe the clinical efficacy of sugar-free particle of Rhodobryum giganteum in treatment angina of diabetic patients with coronary heart disease.Method: A randomized double-blind method was used,105 patients were divided into two groups,and respectively treated with Huixin grass sugar-free particles(66 cases in treatment group) and musk heart-protecting pill(36 patients in control group),the change was observed on angina pain,electrocardiograph(ECG),stop or reduction rate nitroglycerin.Result:The efficiency of treatment group was 92.4% in curing angina and 89.7% in control group.There was no significant difference between treatment and control groups.Electrocardiogram efficiency in the treatment group was 57.6% and the control group was 43.6%(P〈0.05).Reduction rate of nitroglycerin was 83.3% in treatment group and the control group was 79.5%.Conclusion:The sugar-free particle of R.giganteum of angina pectoris has a good effect in treating angina of diabetic patients with coronary heart disease(ECG improved more significantly).
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