儿童特发性血小板减少性紫癜98例临床分析  

Clinical Analysis of 98 Cases with Children Idiopathic Thrombocytopenic Purpura

作　　者：张斌[1] 姚彤[1] 李奇凤[1] 罗新辉[1] 孙荷[1] 

机构地区：[1]新疆维吾尔自治区人民医院,新疆乌鲁木齐830001

出　　处：《医学信息》2012年第8期126-127,共2页Journal of Medical Information

摘　　要：目的分析儿童特发性血小板减少性紫癜癜（idiopathic Thrombocytopenic purpura，ITP）的临床表现及骨髓巨核细胞形态学特点。方法对新疆维吾尔自治区人民医院2009年1月～2011年12月期间，住院的98例ITP病例临床资料进行回顾性分析。结果98例ITP患儿，男61例62．24％），女37例67．76％），急性ITP87例68．78％），慢性ITP11例（11.22％），6岁及以下患儿例76（77.55％），6岁以上22例（22．45％）；有85例66．73％）ITP患儿发病时血小板呈重度、极重度减少，但临床多为轻度出血；ITP组的原、幼及颗粒型MK数明显高于对照组，而产板型MK明显低于对照组：而裸核型MK数量的改变与对照组差异无统计学意义。结论儿童ITP多见于≤6岁的患儿，男女发病机会无差异，该病发病急而临床症状轻。骨髓MK栓查对特发性血小板减少性紫癜确诊有重要意义。Objective To analyze the characteristics and Morphological features of bone marrow megakaryocyte of children idiopathic thrombocytopenic purpura （ITP）. Methods 98 cases of idiopathic thromboeytopenie purpura who were diagnosed in Xinjiang Uygur Autonomous Region People＇s Hospital from 2009 to 2011 were reviewed. Results Among 98 cases （61 male and 37 female）, acute ITP was 87cases （88.78%）,chronic ITP （CITP） were 11 cases （11.22%）. Most of acute ITP in children were less than 6 year old （77.55%）.85cases （86.73%） of ITP had severe thromboeytopenia and most of them showed mild bleeding.Numbers of raw,immature megakaryocytes and granular megakaryocyte in Group ITP were higher than that of the control group,while producing plate-type megakaryocytes was significantly lower than the control group.Numbers of bare karyotype of megakaryoeytes were no significant difference between ITP group and the control group . Conclusion ITP mainly oeured ~〈6-year-old chidren, male and female had equal opportunity. ITP ocured quickly and clinical symptoms were light. Bone marrow MK examination played an important part in diagnosing idiopathic thrombocytopenic purpura.

关 键 词：特发性血小板减少性紫癜 临床分析 儿童 新疆维吾尔自治区人民医院 ITP患儿 骨髓巨核细胞 发病机会 形态学特点 

分 类 号：R554.6[医药卫生—血液循环系统疾病]