深吸气量对慢性阻塞性肺疾病的诊断意义  

The diagnostic significance of inspiratory capacity in chronic obstructive pulmonary disease

作　　者：陈培[1] 杨恂[1] 官和立[1] 张怡[1] 

机构地区：[1]成都大学附属医院呼吸内科,四川成都610081

出　　处：《四川医学》2012年第8期1330-1332,共3页Sichuan Medical Journal

基　　金：四川省卫生厅科研项目(编号:100075)

摘　　要：目的探讨吸入支气管扩张剂后深吸气量(inspiratory capacity,IC)变化率对慢性阻塞性肺疾病(chronic ob-structive pulmonary disease,COPD)的诊断意义。方法对COPD患者组130例,非COPD患者组79例,进行常规肺功能检查,检测到吸入支气管扩张剂后IC前后变化率及1秒率指标。结果以1秒率作为"金标准"计算并得到IC变化率用于判断COPD的ROC曲线,其最佳截点8.4376%,敏感度为86.9%,特异度为83.5%。结论吸入支气管扩张剂后IC变化率对COPD具有较好诊断价值,可用于COPD的诊断。Objective To explore the significance of inspiratory capacity changes in the rate of diagnosis of chronic o]3- structive pulmonary disease after inhalation of bronchodilator. Methods Group of COPD patients with 130 cases, 79 cases of non-COPD patients, all patients underwent conventional pulmonary function tests. Results The IC rate of change is calculated by FEV I/FVC as the ＂gold standard＂, it used to determine the ROC curve of COPD, the best cut-off point of 8. 4376%, a sensitivi- ty of 86. 9% and a specificity of 83.5%. Conclusion IC rate of change in the inhaled bronchodilators have better diagnostic val- ue for COPD, it can be used for the diagnosis of COPD.

关 键 词：慢性阻塞性肺疾病 诊断性试验 深吸气量 

分 类 号：R563.9[医药卫生—呼吸系统]