益母草与马齿苋配伍对小鼠离体子宫收缩的影响  

Effects of uterus contraction of the isolated mouse by the Motherwort and purslane compatibility

作　　者：董自波[1,2] 李超 洪敏[1] 是亚锋 

机构地区：[1]南京中医药大学,南京210046 [2]江苏济川制药有限公司,江苏泰兴225400

出　　处：《中国中医基础医学杂志》2012年第9期979-980,共2页JOURNAL OF BASIC CHINESE MEDICINE

摘　　要：目的:观察益母草与马齿苋配伍对小鼠离体子宫平滑肌收缩性能的影响。方法:雌性小鼠实验前3d,每天皮下注射苯甲酸雌二醇0.2mL/只。实验时颈椎脱臼处死小白鼠,剖宫取出子宫置于与压力换能器相连的麦氏浴槽中,持续供氧,记录正常收缩曲线,然后加入益母草与马齿苋配伍药物或含药血清,记录加药后的子宫收缩曲线。结果:加药或含药血清后的子宫平滑肌肌张力与对照组相比明显增加,表明益母草与马齿苋配伍能增加子宫平滑肌收缩力,加强子宫的收缩能力。结论:益母草与马齿苋配伍直接给药或含药血清均能增加小鼠离体子宫平滑肌的张力,促进子宫收缩,有利于止血。Objective： To observe the effects of Motherwort and purslane compatibility on contraction Property of uterine smooth muscle of Mouse in vitro.Methods： Three days before the experiment,0.2 mL estrodiol benzoatel were given to each feamale mice everyday via subcutaneous injection.The mice were killed through cervica1 dislocation when the beginningof the experiment,the uterus was taken out and placed in culture medium,then put into pressure transducer connected with Michael＇s bath,continued supplying oxygen,the nomna1 curve of the uterine contraction was recorded.Then the curve of the uterine contraction was recorded after the medicine or medicated serum were added.Results： Uterine smooth muscle tension was increased significantly compared with the control group after the medicine or medicated serum were added,indicated Shushen granules can increase uterine smooth muscle contractility and strengthen the uterine contraction.Conclusion： Motherwort and purslane compatibility facilitate hemostasis with increasing the uterine smooth muscle tension and enhancing uterine contraction.

关 键 词：离体子宫 子宫平滑肌 止血 

分 类 号：R285.5[医药卫生—中药学]