我院173例药品不良反应报告分析  

Analysis of 173 Cases of ADR Reports in Our Hospital

作　　者：殷萍萍[1] 王坚[1] 曹辉[1] 张婷婷[1] 

机构地区：[1]东南大学医学院附属南京市第二医院药剂科,南京210003

出　　处：《中国药房》2012年第38期3619-3621,共3页China Pharmacy

摘　　要：目的:了解我院药品不良反应(ADR)发生的特点及规律。方法:对我院2009-2011年上报的173例ADR报告进行回顾性分析。结果:173例ADR报告中,新的严重的ADR占30.64%;门/急诊上报的ADR占29.48%;注射剂是引发ADR的主要剂型,占总例数的78.61%;抗菌药物引发的ADR占30.64%;在临床表现方面,以皮肤及其附件损害最常见,占42.77%。结论:临床应加强抗菌药物使用管理,ADR发生率高的药品应重点监测,以保证药物使用的安全、有效,促进临床合理用药。OBJECTIVE： To investigate the characteristics and regularity of ADR in our hospital. METHODS： 173 ADR cases reported by our hospital during 2009--2011 were analyzed retrospectively. RESULTS： Of 173 ADR reports, new severe ADR ac- counted for 30.64% ; ADR reported by out-patient and emergency department accounted for 29.48% ; most of ADR were caused by injection, accounting for 78.61%; antibiotic-induced ADR accounted for 30.64%; main clinical manifestations were lesion of skin and appendants, accounting for 42.77%. CONCLUSION： Great importance should be attached to antibiotic management and moni- toring of drugs with high incidence of ADR to guarantee the safe and effective use of drugs in the clinic.

关 键 词：药品不良反应 回顾性分析 合理用药 

分 类 号：R969.3[医药卫生—药理学]