三种清洁手术围手术期抗菌药物的使用与切口感染的相关性分析  

The correlation between the use of antibiotics during perioperative period and incision infection in three kinds of clean operation

作　　者：兰顺[1] 叶冬梅[1] 刘柳梅[2] 

机构地区：[1]广西壮族自治区人民医院药学部,南宁530021 [2]广西医科大学药学院

出　　处：《中国临床新医学》2012年第9期848-852,共5页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的分析三种清洁手术围手术期抗菌药物的使用与切口感染的相关性。方法调查广西壮族自治区人民医院2011-01～2011-03(A组)及2012-01～2012-03(B组)的乳腺、甲状腺、疝气等三种清洁手术围手术期抗菌药物的预防使用情况及切口感染的发生率,并对两者的相关性进行分析。结果 344例清洁手术中,A组187例的抗菌药物使用率分别为乳腺手术95.83%(46/48)、甲状腺手术100.0%(61/61)、疝气手术100.00%(78/78);B组157例的抗菌药物使用率分别为乳腺手术5.41%(2/37)、甲状腺手术6.98%(3/43)、疝气手术31.17%(24/77)。A组的抗菌药物使用率明显高于B组(P<0.01)。A、B两组切口感染的发生率均为0.00%,差异无统计学意义(P>0.05)。结论清洁手术围手术期抗菌药物的使用与切口感染的发生率不存在相关性,无高危因素患者行清洁手术,围手术期可不用抗菌药物预防感染。Objective To analyze the correlation between the use of antibiotics during perioperative period and incision infection in three kinds of clean operation. Methods An investigation on the patient history and the use of antibiotics during perioperative period in the patients of breast, thyroid and hernia surgery in people＇ s hospital of Guangxi Zhuang Autonomous Region from January to March 2011 （group A） and January to March 2012 （group B） was carried, and the correlation between the use of antibiotics and incision infection was analyzed. Results In 344 eases of clean operation,the usage rate of antibiotics in group A （n = 187） was 95. 83% （46/48） in breast surgery, 100. 00% （61/61） in thyroid surgery, 100. 00% （78/78） in hernia surgery, and in group B （ n = 157 ） the usage rate was 5.41% （2/37） in breast surgery, 6. 98% （3/43） in thyroid surgery, 31.17% （24/77） in hernia surgery. The usage rate of antibiotics in group A was higher than that in group B, there was statistically significant difference （P 〈0. 01 ）. The incidence of incision infection of group A and group B were 0. 00% ,there was no statistically signif- icant difference （ P 〉 0. 05 ）. Conclusion There was no correlation between the use of antibiotics and incision infec- tion rate in perioperative period of cleaning operation. Antibiotics can be avoided in the patients with no high risk fac- tors in perioperative period of cleaning operation.

关 键 词：清洁手术 抗菌药物 围手术期 切口感染 

分 类 号：R97[医药卫生—药品]