红花中羟基红花黄色素A的闪式提取工艺研究  

Optimization of Smashing Tissue Extraction of Hydroxyl Safflor Yellow A from Carthamus Tinctorius L.

作　　者：王玥[1] 杜守颖[1] 吴清[1] 肖瑶[1] 武慧超[1] 陆显进[1] 魏长玲[1] 林宏英[1] 戎堃[1] 袁航[1] 李慧云[1] 

机构地区：[1]北京中医药大学中药学院.中药基础与新药研究北京市重点实验室,北京100102

出　　处：《时珍国医国药》2012年第9期2144-2145,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国家自然科学基金面上项目(No.81073057);教育部博士点基金项目(No.20090013110007);北京中医药大学复方中药制药研究创新团队(No.2011-CXTD-13);国家重点实验室开放基金项目(No.SKL2010Z0304);重大新药创制项目(No.2009ZX09502-008)

摘　　要：目的研究闪式提取红花中羟基红花黄色素A的最佳工艺条件。方法以提取液中羟基红花黄色素A的含量为指标,采用正交试验设计,对闪式提取的影响因素进行考察,并在提取率、提取时间、耗电量等方面与文献报道的方法进行比较。结果最佳提取工艺是以40倍水为溶剂,闪式提取2 min,100 V电压。结论该法工艺简单、经济、提取率较高,可为中药红花的开发利用提供参考。Objective To study the feasibility and process conditions of extracting Carthamus tinctorius L.by smashing tissue extraction.Methods To measure the content of Hydroxyl safflor yellow A extracting solution by HPLC using orthogonal design to analyze the effective factors of the smashing tissue extraction and to compare with other methods in extraction rate,extraction time and electricity consumption.Results The optimized conditions using water as solvent were liquid-material ratio of 40： 1（ml·g^-1）,extraction time of 2 min,120 V voltage.Conclusion Smashing tissue extraction is an effective method to extract Hydroxyl safflor yellow A from Carthamus tinctorius L.

关 键 词：闪式提取 红花 羟基红花黄色素A 正交试验 

分 类 号：R284.2[医药卫生—中药学]