基于多项Logit模型的绝经后骨质疏松症高危人群危险因素分析  

Analysis on Risk Factors of Postmenopausal Women with High-risk of Osteoporosis Based on Multinomial Logit Model

作　　者：谢雁鸣[1] 李建鹏[1] 崔庆荣[1] 吕伟嘉[2] 易丹辉[2] 虞鲲 康澍[4] 田峰[1] 

机构地区：[1]中国中医科学院中医临床基础医学研究所,北京100700 [2]中国人民大学统计学院,北京100872 [3]上海市大华医院,上海200237 [4]北京中医药大学东直门医院,北京100700

出　　处：《世界科学技术-中医药现代化》2012年第4期1835-1840,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金面上项目(30873339):基于非齐性Markov model建立病证结合的绝经后骨质疏松证早期风险评估模型;负责人:谢雁鸣

摘　　要：目的:筛选绝经后骨质疏松症高危人群的危险因素。方法:对1740例绝经后骨质疏松症高危者进行双能X线吸收仪骨密度检测,对符合标准者进行现场问卷调查。采用多分类Logistic回归方法分析绝经后骨质疏松症与危险因素之间的定量关系,建立多项Logit模型。结果:模型最终引入的变量有绝经年限、体重指数、鱼类膳食、是否变矮、是否绝经和生产次数。结论:绝经是绝经后骨质疏松症的主要危险因素,低体重指数也是绝经后骨质疏松症发病的危险因素;鱼类膳食和绝经后骨质疏松症发病之间均存在负相关性,是绝经后骨质疏松症的保护性因素。This study was aimed to screen out risk factors associated with occurrence of postmenopausal osteoporosis. All 1740 women with high postmenopausal osteoporosis risk factors were selected to accept the bone mineral density examination. Then, a screening questionnaire survey was conducted. The quantitative relation between risk factors and postmenopausal osteoporosis was analyzed with multinomial logistic regression. The results showed that including duration of menopause, body mass index, fish diet, whether height shorten, whether menopause, and previous obstetric history. It was concluded that menopause was a main risk factor for PMOP, and low body mass index was also a risk factor for postmenopausal osteoporosis. A negative correlation exists between postmenopausal osteoporosis and fish diet, which is a protective factor for PMOP

关 键 词：绝经后骨质疏松症 危险因素 多项Logit模型 

分 类 号：R681[医药卫生—骨科学]