脐静脉血流量在产前评估双胎输血综合征中的应用  

The value of umbilical venous volume flow in prenantal assessment of twin-twin transfusion syndrome

作　　者：刘志红[1] 蔡爱露[1] 

机构地区：[1]中国医科大学附属盛京医院超声科,沈阳110004

出　　处：《中国医疗前沿》2012年第17期5-6,9,共3页China Healthcare Innovation

摘　　要：目的探讨胎儿脐静脉血流量(UVF)在产前评估双胎输血综合征(TTTS)中的应用价值。方法以22对产前诊断为TTTS双胎作为实验组,选取22对非TTTS的单绒毛膜双羊膜囊双胎(MCT)作为对照组。应用多普勒超声获取胎儿脐静脉血流频谱并测得此处胎儿脐静脉的横截面积,计算每个胎儿绝对的脐静脉血流量UVF、经体重校正的脐静脉血流量(UVF/kg)、每一对胎儿间UVF/kg的差值(ΔUVF/kg)、每一对胎儿间UVF/kg的比(R/D-UVF/kg)。对一对胎儿间及两组胎儿间脐静脉血流量参数进行比较。结果实验组受血儿与供血儿的脐静脉血流量差异及实验组和对照组的脐静脉血流量参数差异均有统计学意义(P<0.05)。实验组中受血儿的UVF和UVF/kg明显高于供血儿;实验组ΔUVF/kg和R/D-UVF/kg亦明显高于对照组。结论胎儿脐静脉血流量的差异反映了TTTS胎儿间不平衡的血流状态,有助于TTTS的产前诊断及评估。Objectives To evaluate the value of umbilical venous volume flow（UVF） in the prenantal assessment of twintwin transfusion syndrome（TTTS）.Methods Twenty-two pair of twins diagnosed as TTTS were selected as experimental group,and 22 pairs of Monochorionic twins（MCT） as control group.In experimental group,absolute UVF,UVF corrected for estimated fetal weight（UVF/kg）,intertwin difference（ΔUVF/kg） and recipient to donor ratio（R/D-UVF/ kg） were calculated.Parameters for UVF were compared with control group.Results In experimental group,UVF and UVF/kg were all higher in recipients than in donors in both twins（in recipients,83.3ml/min and 156.8ml/kg/min;in donors,44.3ml/min and 116.4ml/kg/min）.The deference of experimental group and control group in ΔUVF/Kg and R/D-UVF/Kg were significant（P 0.05）.Conclusion In TTTS,UVF is significantly higher in recipients than in donors.The deffrence of umbilical venous volume flow of TTTS are higher than MCT without TTTS.

关 键 词：脐静脉血流量 单绒毛膜双胎 双胎输血综合征 

分 类 号：R714.5[医药卫生—妇产科学]