反流性咽喉炎治疗体会60例  

Clinical study on laryngopharyngeal reflux

作　　者：薛建荣[1] 蒋星[2] 仇翼[2] 何梦月[2] 

机构地区：[1]江苏省常州市第三人民医院耳鼻咽喉科,常州213001 [2]江苏省常州市第三人民医院药剂科,常州213001

出　　处：《中国眼耳鼻喉科杂志》2012年第5期301-302,305,共3页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘　　要：目的研究反流性咽喉炎的发病机制,探索最佳治疗方案。方法选取反流性咽喉炎患者60例,随机分为两组:治疗组30例和对照组30例。对照组以奥美拉唑治疗。治疗组以奥美拉唑联合碳酸氢钠雾化治疗,服药3个月后随访1年。结果治疗组有效率86.6%,对照组有效率73.3%,治疗组明显优于对照组(P<0.05)。结论胃食管反流是反流性咽喉炎最重要的致病因素,奥美拉唑联合碳酸氢钠雾化治疗可有效改善反流性咽喉炎的症状与体征。Objective To study the pathophysiological mechanism of laryngopharyngeal reflux （LPR） and to investigate its best therapy. Methods Sixty patients of LPR were divided into two groups with 30 cases in each. Antacid treatment with omeprazole and spray with sodium bicarbonate was given in the study group and only antacid treatment with omeprazole was given in the control group. All patients were followed up for 1 year. Results Twenty-six cases were effective （86.6%） in study group and 22 cases （73.3%） in control group. Conclusions Gastroesophageal reflux was the most important cause of LPR, the symptoms and signs of which could be healed by antacid treatment with omeprazole and spray with sodium bicarbonate. （Chin J Ophthalmol and Otorhinolaryngol ,2012 ,12 ：301-302 ,305 ）

关 键 词：反流性咽喉炎 胃食管反流 发病机制 治疗 

分 类 号：R766[医药卫生—耳鼻咽喉科]