心脏移植术后长期存活病例移植物血管病变的临床分析  

Clinical analysis of transplant vasculopathy of long-term survival patients after heart transplantation

作　　者：李君权[1] 安守宽[1] 章佰承[1] 乔友进[1] 夏求明[1] 

机构地区：[1]哈尔滨医科大学附属第二医院心外科,黑龙江哈尔滨150081

出　　处：《哈尔滨医科大学学报》2012年第4期364-366,369,共4页Journal of Harbin Medical University

摘　　要：目的明确心脏移植术后患者冠状动脉病变及其对患者长期存活的影响。方法对1992年4月至2000年4月在哈尔滨医科大学附属第二医院接受心脏移植超过10年的4例患者进行了回顾性分析。结果 4例患者都发生不同程度的移植物血管病变,且10年后4例患者心脏射血分数(EF)全部﹥50%并心功能良好。其中1例存活时间超过了18年,是中国心脏移植术后存活时间最长的,也是亚洲现存心脏移植术后存活时间最长的。结论心脏移植术后长期存活并维持其供体心脏的正常的血流动力学功能是可能的,术后移植物血管病变是同种异体心脏移植术后的常见并发症,积极地预防有利于心脏移植患者的长期存活。Objective To analyse the influence of the transplant vasculopathy after heart trans- plantation on long-term survival patients. Methods We analyzed clinical outcomes in the group of 4 patients （ 〉 10 years）who have undergone heart transplantation at The Second Affili- ated Hospital of Harbin Medical University from April 1992 to April 2000. Results There was different degree of transplant vasculopathy in the long-term survival patients. Their left ventric- ular ejection fractions were more than fifty percent and cardiac function kept well. The longest survival patients was more than 18 years after transplantation who was the longest one in China and was the longest heart transplantation patient alive in Asia. Conclusion Long-term survi- vors could maintain normal hemodynamic function of their allografts and enable long-term sur- vival after cardiac transplantation. Transplant vasculopathy are more common after transplanta- tion. Aggressive preventive and therapeutic measures are essential to limit the risk factors for development of complications.

关 键 词：心脏移植 长期存活 移植物血管病变 

分 类 号：R654.2[医药卫生—外科学]