无创性左心功能不全诊断多参数相关性研究  

Related Research on Multi-parameter of Cardiac Dysfunction

作　　者：唐杨章[1] 高华康[1] 程训民[1] 祖秋菊[1] 朱晴[1] 王广川[1] 李晓波[1] 

机构地区：[1]安徽省淮北市人民医院心内科,235000

出　　处：《实用心脑肺血管病杂志》2012年第10期1614-1615,共2页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的探究心功能不全患者血浆B型脑钠肽(BNP)水平与心功能分级、左室射血分数(LVEF)、P波终末电势(PtfV1)等多参数的相关性。方法对94例慢性心功能不全患者就诊后24h内取静脉血测定血浆BNP,并行超声心动图、心电图检查,分析血浆BNP与NYHA心功能分级、LVEF、PtfV1之间的关系。结果心功能Ⅰ、Ⅱ、Ⅲ、Ⅳ级患者血浆BNP水平逐级增加(P<0.05);BNP与LVEF呈负相关,PtfV1值大的患者血浆BNP显著大于PtfV1小的患者,BNP与PtfV1、心功能分级三者均呈正相关。结论 (1)血浆BNP水平与传统的评价心功能指标有明确相关性,可作为临床评价心功能状况的良好指标;(2)超声心动图LVEF值不能反映部分左室舒张功能;(3)床边心电图PtfV1≥0.03可作为左心功能不全评估的初步依据。Objective To explore the relationship between Plasma brain natriuretic peptide （BNP） levels and cardiac functional grading, left ventricular ejection fraction （LVEF） and p -wave terminal force -vl （PtfV1） in patients with heart fail- tire. Methods After determination of plasma BNP, echocardiography and electrocardiographic examination in 94 patients with chronic heart failure patients visited within 24 hours, the relationship between BNP levels and NYHA classification of cardiac function, LVEF and PtfV1 were analyzed. Results Plasma BNP levels increased progressively in patients with Cardiac function grade Ⅰ , Ⅱ, Ⅲ and Ⅳ （P〈0. 05） ; BNP and LVEF were negative correlated, the BNP values of those patients with higher PtfV1 are significantly higher than those of patients with lower PtfV1. Therefore, BNP and PtfV1, classification of cardiac func- tion were positively correlated as well. Conclusion （ 1 ） Plasma BNP levels and traditional indicators of cardiac function have a clear relevance. It can be used as a good indicator of clinical evaluation of cardiac function; （2） LVEF cannot be reflected by echocardiography very well; （3） PtfV1 ≥ 0. 03 bedside ECG can be used as a preliminary basis to assess left ventricular dys- function.

关 键 词：心脏 脑钠肽 每搏输出量 P波终末电势 

分 类 号：R541[医药卫生—心血管疾病]