后扩张在老年患者冠状动脉钙化病变PCI术中的应用价值  

Observation on Therapeutic Effects of Postdilatation for Elderly Patients with Coronary Artery Calcification Lesion

作　　者：董平栓[1] 陈瑞晓[1] 王红雷[1] 李志娟[1] 王可[1] 杨旭明[1] 王绍欣[1] 李转珍[1] 范喜梅[1] 杜来景[1] 

机构地区：[1]河南科技大学第一附属医院,河南洛阳471003

出　　处：《河南科技大学学报（医学版）》2012年第3期190-193,共4页Journal of Henan University of Science & Technology:Medical Science

基　　金：2010年洛阳市科技攻关计划资助项目(1001011A-2)

摘　　要：目的观察后扩张在老年患者冠状动脉钙化病变经皮冠状动脉介入治疗(PCI)术中应用的疗效和安全性。方法选择PCI血管造影成功的老年钙化病变患者124例,随机分为后扩张组62例和常规置入对照组62例,观察两组患者PCI术中并发症发生率及住院期间及术后1 a支架内血栓、再狭窄和主要不良心脏事件(MACE)发生率。结果后扩张组和常规植入组患者PCI术中并发症发生率两组间比较无统计学差异(6.5%、4.8%,P>0.05);1 a时的随访结果显示,后扩张组的主要不良心血管(MACE)事件发生率较对照组降低(4.8%、12.9%,P<0.05);支架内血栓和支架内再狭窄发生率较常规置入组均明显减少(1.6%、4.8%;4.4%、14.3%,P<0.05),差异有显著意义。结论在老年钙化病变患者PCI术中应用后扩张治疗安全、有效,能够降低支架内血栓、再狭窄和MACE发生率。Objective To observe the clinical therapeutic effect and security of adjunctive balloon postdilatation applying to percutaneous coronary intervention for elderly patients with coronary artery calcification lesion. Methods 124 elderly patients with coronary artery calcification lesion and successful angiograph in our hospital were randomly divided into the post-dilatation deployment group （n = 62） and the control group （n = 62）. The complications of intraoperative and stent thrombosis, stent restenosis and major adverse cardiac events （MACE） within hospitalization and one year were observed. Results Intraoperative complications were similar between the two groups （6. 5% vs 4. 8% , P 〉 0.05 ） ; stent thrombosis, stent restenosis, major adverse cardiac events were significantly lower in post-dilatation deployment group than in control group at 1 year. （1.6% vs4.8%; 4.4% vs 14.3% ;4.8% vs 12.9%. all P 〈 0.05）. Conclusion Routine post-dilatation approach is safe and effective for elderly patients with coronary artery calcification lesion undergoing PCI. It is assosiated with lower stent thrombosis, stent restenosis, major adverse cardiac events and improved prognosis.

关 键 词：后扩张 冠状动脉疾病 老年 经皮冠状动脉介入治疗 钙化病变 

分 类 号：R543.3[医药卫生—心血管疾病]