微波辐射对甲苯磺酸催化合成对羟基苯甲酸乙二醇单酯  

Synthesis of mono-4-hydroxybenzoic acid ethylene glycol ester catalyzed by p-toluene sulfonic acid under microwave radiation

作　　者：杨晓军[1] 冯小丽[1] 张谋真[1] 

机构地区：[1]延安大学化学与化工学院,陕西延安716000

出　　处：《工业催化》2012年第9期59-61,共3页Industrial Catalysis

基　　金：陕西省科技厅自然科学基金(SJKY2010048)资助项目;陕西省教育厅自然科学基金(2010JK912)资助项目

摘　　要：在微波辐射下,研究了以对甲苯磺酸为催化剂,对羟基苯甲酸和乙二醇为原料合成对羟基苯甲酸乙二醇单酯的工艺条件。用红外光谱分析和核磁共振光谱等方法对产物的结构进行表征,考察微波辐射功率、催化剂用量、酸醇物质的量比以及微波辐射时间对酯化率的影响。结果表明,合成对羟基苯甲酸乙二醇单酯的优化条件为:微波辐射功率500 W,酸醇物质的量比为1∶3.5,催化剂用量0.28 g,微波辐射时间20 min,此条件下,酯化率达92.1%。Mono 4-hydroxybenzoic acid ethylene glycol ester was synthesized by using 4-hydroxybenzoic acid and ethylene glycol as the raw materials and p-methyl benzene sulfonic acid as the catalyst under microwave radiation. The product was characterized by IR and NMR. The influence of microwave radiation power and time, catalyst dosage, and molar ratio of the reactants on the yield was investigated. The results showed that the esterification yield of 92.1% was attained under the optimal synthesis condition as fol- lows ： microwave radiation power 500 W, catalyst dosage 0.28 g, molar ratio of the reactants 1 ： 3.5 and mi- crowave radiation time 20 min.

关 键 词：精细化学工程 微波辐射 对甲苯磺酸 对羟基苯甲酸乙二醇单酯 

分 类 号：TQ426.94[化学工程] O643.36[理学—物理化学]