斑点追踪技术定量评价肥厚型心肌病左心房容积与功能  

Quantitative Assessment of Left Atrial Volume and Function in Patients with Hypertrophic Cardiomyopathy with Speckle Tracking Echocardiography

作　　者：李潭[1] 杨军[1] 孙丹丹[1] 马春燕[1] 陈昕[1] 刘爽[1] 白洋[1] 

机构地区：[1]中国医科大学附属第一医院心血管超声科,沈阳市110001

出　　处：《中国超声医学杂志》2012年第9期802-805,共4页Chinese Journal of Ultrasound in Medicine

基　　金：辽宁省自然科学基金(No.20092134)

摘　　要：目的应用斑点追踪超声心动图(STE)定量评价肥厚型心肌病(HCM)左心房容积与功能改变,探讨该技术测量左心房容积与功能的可行性。方法选择HCM组34例和正常对照组35例。应用STE和实时三维超声心动图(RT-3DE)测量和计算左心房容积与功能指标。结果与正常组相比,HCM组左心房LAVmax、LAVp和LAVmin显著增加,LAPEF、LATEF、EI减小而LAAEF增加(P均<0.01)。STE和RT-3DE测得的LAVmax、LAVp、LAVmin、LAPEF、LAAEF、LATEF、EI呈高度正相关(P均<0.01),STE测量时间显著短于RT-3DE(P<0.01)。结论 HCM组左心房容积增大,被动射血功能、扩张能力和整体射血功能减低,主动射血功能代偿性增强。STE技术为评价左心房容积与功能提供了可行、有效、便捷的新方法 。Objective To assess the change of left atrial volume and function in patients with hypertrophic car-diomyopathy （HCM） using speckle tracking echocardiography （STE） quantitatively and discuss its feasibility in asses-sing left atrial volume and function. Methods 34 subjects with HCM and 35 normal controls were examined. STE and real time three dimensional echocardiography（RT-3DE） were used to measure and calculate the left atrial volume and function. Results Compared with the normal group, LAVmax,LAVp,LAVImin were increased significantly in HCM group, LAPEF, LATEF and EI were decreased but LAAEF was increased（all P〈0.01）. Excellent correlation of LAVmax, LAVp,LAVmin,LAPEF, LATEF, EI were noted between STE and RT-3DE（all P〈0.01 ）. Measurement time with STE was shorter than that with RT-3DE（P〈0.01）. Conclusions In HCM group, left atrial volume are in-creased, passive ejection function, expansion function and total ejection function are decreased whereas the active ejec-tion function is increased. STE provides a new method in assessing left atrial volume and function.

关 键 词：斑点追踪技术 肥厚型心肌病 左心房功能 

分 类 号：R542.2[医药卫生—心血管疾病] R540.45[医药卫生—内科学]