肿瘤急性术后高血压患者术后出血事件相关因素分析  

Analysis of Risk Factors for Postoperative Hemorrhage in Acute Postoperative Hypertensive Patients after Tumorectomy

作　　者：汪道峰[1] 王智[1] 娄宁[1] 

机构地区：[1]华南肿瘤学国家重点实验室//中山大学肿瘤防治中心ICU,广东广州510060

出　　处：《中山大学学报（医学科学版）》2012年第4期508-511,共4页Journal of Sun Yat-Sen University:Medical Sciences

基　　金：广东省科技计划项目(2010B030700051)

摘　　要：【目的】探讨肿瘤急性术后高血压(APH)患者术后出血事件的相关危险因素。【方法】采用回顾性调查方法 ,对528名肿瘤根治术后急性高血压患者进行分析。【结果】肿瘤根治术后急性高血压患者术后出血发生率为12.1%(64例),单因素分析表明:性别(P=0.001)、嗜烟(P=0.020)、手术时间(P=0.012)、手术类型(P=0.003)、启动降压治疗时的舒张压水平(P=0.005)是其危险因素,多因素分析提示:手术时间是术后出血事件发生的独立危险因素(P=0.040)。【结论】启动降压治疗时血压水平可能与术后出血事件无关,手术时间可能与术后出血事件发生密切相关。[ Objective ] To discuss the risk factors for postoperative hemorrhage in acute postoperative hypertensive patients after tumorectomy. [Methods] The clinical data of 528 patients receiving tumorectomy, which happened postoperative hypertension were analyzed retrospectively. [Results] The incidence of postoperative hemorrhage was 12.1%. The univariate analysis showed that the major prognostic factors for postoperative hemorrhage were sex （P= 0.001）, smoking （P = 0.020）, operative time （P= 0.012）, operative type （P = 0.003）, and diastolic blood pressure level when hypertension was treated （P = 0.005 ）. Muhivariant analysis show that only the operative time was identified as the independent risk factor associated with the occurrence of postoperative hemorrhage （P=0.040）. [ Conclusions] The blood pressure level when hypertension was treated may be not related with postoperative hemorrhage, whereas the operative time may be related with postoperative hemorrhage in postoperative hypertensive patients.

关 键 词：急性术后高血压 出血 治疗 肿瘤 

分 类 号：R544.1[医药卫生—心血管疾病]