曲靖市某院住院儿童血培养病原菌分布及耐药性分析  

Distribution and drug resistance analysis of blood culture pathogens of hospitalized children in a hospital of Qujing city

作　　者：周俊萍 杨本寿 林丽萍 

机构地区：[1]曲靖医学高等专科学校生化教研室,云南曲靖655000

出　　处：《现代医药卫生》2012年第18期2753-2754,共2页Journal of Modern Medicine & Health

基　　金：云南省教育厅科学研究基金资助项目(2010Y226)

摘　　要：目的了解曲靖市某院住院儿童血培养病原菌的分布及耐药情况。方法分析2010年3月至2011年12月曲靖市某医院住院患儿送检的阳性标本,采用全自动细菌分析仪进行病原学鉴定及药敏试验。结果 4 020份血标本共分离出病原菌430株,阳性率为10.70%,其中革兰阳性菌233株,占54.19%,以表皮葡萄球菌和溶血葡萄球菌为主;革兰阴性菌194株,占45.12%,以大肠埃希菌、肺炎克雷伯菌为主。结论该院住院儿童血培养分离病原菌以革兰阳性菌为主,临床上应重视住院儿童血培养病原菌的耐药情况,加强耐药性监测,合理使用抗菌药物。Objective To understand the distribution and drug resistance of blood culture pathogens of hospitalized children in a hospital of Qujing city.Methods The positive detection samples of hospitalized children in a hospital of Qujing city from March 2010 to December 2011 were analysed.The pathogens identification and the drug susceptibility testing were used by the fully automatic bacterial analyzer.Results 430 strains of pathogens were isolated from 4020 blood samples with the positive rate of 10.70 %.Among them,233 strains were Gram positive bacteria,accounting for 54.19%,which was dominated by Staphylococcus epidermidis and Staphylococcus haemolyticus;194 strains were Gram negative bacteria,accounting for 45.12 %,which was dominated by Escherichia coli and Klebsiella pneumoniae.Conclusion Gram positive bacteria are the main blood culture pathogens isolated from hospitalized children in this hospital.The drug resistance of blood culture pathogens in hospitalized children should be clinically paid attention to.The drug resistance monitoring should be strengthened and the antimicrobial agents should be rationally used.

关 键 词：儿童 住院 革兰氏阳性菌 葡萄球菌属 革兰氏阴性菌 微生物敏感性试验 抗药性 细菌 培养基 条件性 抗菌药 

分 类 号：R446.5[医药卫生—诊断学]