宫颈细胞学ASC的临床评价及处理探讨  

Clinical Evaluation and Processing Discussion of Cervical Cytology ASC

作　　者：李微微[1] 谢芳[1] 毛瑛玉[2] 李珍[1] 黄梅秀[1] 

机构地区：[1]福建医科大学附属闽东医院妇产科,福安355000 [2]福建医科大学附属闽东医院病理科,福安355000

出　　处：《中国医药导刊》2012年第9期1577-1578,共2页Chinese Journal of Medicinal Guide

基　　金：宁德市科学技术计划项目(编号20080050)资助

摘　　要：目的:探讨宫颈细胞学检查为ASC(非典型鳞状上皮细胞)的临床评价及进一步处理方法。方法:2008年1月～2011年1月我院细胞学检查为ASC的妇女386例,307例行阴道镜检查及活检,其中113例同时进行HPV-DNA检测。结果:307例ASC患者病理诊断为炎症、CINⅠ、CINⅡ、CINⅢ、SCC、湿疣的百分比分别为65.15%、11.08%、10.75%、10.10%、0.98%、1.95%。HPV检测阳性率为55.75%,HPV阳性组病理为CIN的检出率为65.08%,明显高于阴性组的36%(P<0.01)。结论:细胞学结果为ASC患者,宫颈病变占相当的比率,应高度重视,尤其是HPV阳性病例。进一步行阴道镜检查和镜下活检是比较恰当的一种处理方式,可减少癌前病变的漏检。Objective：To investigate the clinical significance and further treatment.of cervical cytology as ASC（Atypical Squamous Cells of undetermined significance）.Methods：386 cases of ASC patients in our hospital from January 2008 to January 2011 were certified by gynecological cytology reports,307 cases underwent colposcopy evaluation and biopsy,of whom 113 patients underwent HPV-DNA detection.Results：The respective percentage of inflammation,CIN Ⅰ,CIN Ⅱ,CIN Ⅲ,SCC,cervical condyloma certified by pathological diagnosis among the 307 cases of ASCpatients were 65.15%,11.08%,10.75%,10.10%,0.98%,1.95%.And HPV detection positive rate was 55.75%.The detection rate of CIN pathology in HPV-positive group was 65.08%,which was significantly higher than the negative group of 36%（P〈0.01）.Conclusion：Cervical lesions among the patients with cytology results of ASC accounted for a ratio should pay great attention,especially HPV positive cases.That further should do the colposcopy inspection and the microscopic biopsy is more appropriate treatment of a way.That can reduce precancerous lesions miss.

关 键 词：ASC 阴道镜 宫颈上皮内瘤变 人乳头瘤病毒 

分 类 号：R737.33[医药卫生—肿瘤]