呼出气一氧化氮在儿童呼吸道疾病中的应用进展  

Advances in application of fractional exhaled nitric oxide in children＇s respiratory diseases

作　　者：骆学勤(综述)[1] 罗健(综述)[1] 符州(审校)[1] 

机构地区：[1]重庆医科大学附属儿童医院呼吸中心,400014

出　　处：《国际儿科学杂志》2012年第5期437-440,共4页International Journal of Pediatrics

摘　　要：NO是人体内重要的信号因子，存在于正常人的呼出气中。各种呼吸道炎症性疾病均可导致呼出气NO增高，尤其是嗜酸性粒细胞性炎症。呼出气NO测定能直接反映气道炎症，具有无创、重复性好、易操作等优势，有助于临床对反复喘息、慢性咳嗽等呼吸道常见症状的病因鉴别，有助于对支气管哮喘等多种疾病的诊断、判断病情及预后，对于儿童呼吸道疾病的管理具有重要价值。NO is an important signal factor existing in expiratory air of normal person. Different kinds of airway inflammation can cause the increase of NO, especially eosinophilic inflammation. Fractional exhaled nitric oxide （FENO） can result in airway inflammation, which is noninvasive, repeatable and easily performed. It can be very helpful in the diagnosis and differential diagnosis of airway symptoms such as recurrent wheezing and chronic cough. It can also help determine the state of the disease and prognosis. It is a very useful tool in the assessment and management of airway diseases, especially asthma.

关 键 词：呼出气一氧化氮 儿童 呼吸道疾病 

分 类 号：R562.25[医药卫生—呼吸系统]