急性心肌梗死患者D-二聚体、cTnT及心肌酶谱联合检测的临床意义  

Clinic Significance of Checkout of Plasma D-Dimer,cTnT and Myocardial Enzyme Spectrum in Patient with Acute Myocardial Infarction(AMI)

作　　者：郑丽[1] 钟硕贤[1] 胡素华[1] 

机构地区：[1]中山大学附属第六医院,广东广州510655

出　　处：《广东微量元素科学》2012年第7期28-31,共4页Trace Elements Science

摘　　要：为探讨急性心肌梗死患者D-二聚体、肌钙蛋白及心肌酶谱联合检测的临床意义,选择30例健康者(对照组)和100例患者(病例组)进行D-二聚体、肌钙蛋白及心肌酶谱(AST、LDH、CK、CK-MB)检测,并把100例患者(病例组)分为3组,分别为36例AMI组,34例不稳定型心绞痛(UAP)组,30例稳定型心绞痛(SAP)组。结果表明,AMI组及UAP组中D-二聚体、肌钙蛋白及心肌酶谱(AST、LDH、CK、CK-MB)的升高程度较SAP组和健康对照组显著增高(P<0.05);AMI组肌钙蛋白(cTnT)较UAP组明显增高(P<0.05);UAP组肌钙蛋白(cTnT)较对照组明显增高(P<0.05);D-二聚体、肌钙蛋白及心肌酶谱(AST、LDH、CK、CK-MB)的升高程度与心肌梗死的面积正相关(P<0.01)。提示D-二聚体、肌钙蛋白及心肌酶谱(AST、LDH、CK、CK-MB)联合检测有助于急性心肌梗死诊断的提高。To checkout clinic significance of plasma D - dimer, cTnT and Myocardial enzyme spectrum in patient with myocardial infarction （AMI）, D -dimer, troponin and myocardial enzyme spectrum （AST, LDH, CK, CK - MB） in 30 persons of control group and 100 patients were tested, and 100 patients were divided into 3 groups, 36 cases of AMI group, 34 patients with unstable angina pectoris （UAP） group, 30 cases of stable angina pectoris （SAP） group. The results show that AMI group and UAP group D - two dimers, troponin and myocardial enzyme spectrum （AST, LDH, CK, CK - MB） increased in SAP group and the healthy control group increased significantly （ P 〈 0. 05 ） ; AMI （cTnT） group of troponin than UAP group increased significantly （P 〈 0. 05 ） ; UAP （cTnT） is the group of troponin as the group were significantly increased （ P 〈 0. 05 ） ; D - two dimers, troponin and myocardial enzyme spectrum （ AST, LDH, CK, CK - MB） elevated level and the area of myocardial infarction is related （ P 〈 0.01 ）. It concludes： D- dimers, troponin and myocardial enzyme spectrum （AST, LDH, CK, CK -MB） joint detection is helpful to the diagnosis of acute myocardial infarction improve.

关 键 词：D-二聚体 CTNT 肌钙蛋白 心肌酶谱 联合检测 心肌梗死 

分 类 号：R542.22[医药卫生—心血管疾病]