高压氧治疗新生儿缺血缺氧性脑病42例临床观察  

Hyperbaric oxygen in treatment of neonatal hypoxic ischemic encephalopathy of clinical observation of 42 cases

作　　者：韩康 

机构地区：[1]四川省内江市中医院新生儿科,641000

出　　处：《中国实用医药》2012年第26期13-14,共2页China Practical Medicine

摘　　要：目的研究高压氧治疗新生儿缺血缺氧性脑病的临床疗效。方法选择新生儿缺血缺氧性脑病患儿,随机分为高压氧治疗的观察组和常规治疗的对照组,观察症状恢复情况、脑血管指标以及治疗效果。结果观察组意识、肌张力和吸吮反射恢复时间均短于对照组,神经行为评分、GH和IGF-1水平高于对照组,大脑中动脉和基底动脉的流速明显慢于对照组。结论高压氧治疗能够提高治疗的总有效率、缩短症状恢复时间、促进GF和IGF-1的表达,是治疗新生儿缺血缺氧性脑病行之有效的方法。Objective Study of hyperbaric oxygen in treatment of neonatal hypoxic ischemic encepha- lopathy clinical curative effect. Methods Selection of neonatal hypoxic ischemia in pediatric patients, random- ly divided into hyperbaric oxygen therapy in the observation group and conventional therapy in the control group, observation of two groups of patients with symptomatic recovery, cerebral vascular index and therapeutic effect. The observation group consciousness, muscle tension and the sucking reflex recovery time was shorter than that in the control group, neurobehavioral score, GF and IGF-1 levels higher than those in the control group, middle cerebral artery and base arterial flow velocity was significantly slower than that of the control group. Conclusion Hyperbaric oxygen therapy can improve the treatment of total efficiency, shorten the dura- tion of symptoms, promote the recovery time of GF and IGF-1 expression, is the treatment of neonatal hypoxic ischemic eneephalopathy effective method.

关 键 词：高压氧 缺血缺氧性脑病 新生儿 

分 类 号：R473.72[医药卫生—护理学]