中医特色疾病管理模式干预抑郁症随机对照研究  

Randomized Controlled Study of Depression Using Disease Management of Traditional Chinese Medicine Model

作　　者：范竹青[1] 陈杰[2] 裴音[2] 杨婧[2] 张捷[2] 

机构地区：[1]首都医科大学附属复兴医院针灸科,北京100045 [2]首都医科大学附属北京中医医院身心医学科,北京100010

出　　处：《中国中医药信息杂志》2012年第9期7-10,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：首都医学发展基金(中医药类;SF2007-Ⅲ-26)

摘　　要：目的应用疾病管理理论与技术,探索适宜抑郁症患者的中医特色疾病管理模式,观察其在抑郁症中应用的有效性。方法以首都医科大学附属北京中医医院针灸科抑郁专台2010年5-8月就诊符合纳入标准的60例患者为观察对象,随机分为管理组和对照组。管理组接受中医特色疾病管理,包括综合抗抑郁治疗、抑郁症中医特色教育、定期复诊、评估。对照组以常规诊疗模式接受治疗及定期评估。2组观察评估时间均为24周。分别于治疗前及治疗4、8、12、16、20、24周末观察汉密尔顿抑郁量表(HAMD)、临床疗效总评量表情况。结果管理组在干预第12、16、20、24周末HAMD评分低于对照组(P<0.05或P<0.01)。管理组与对照组在干预第20、24周末严重程度和总体进步评分组间差异有统计学意义(P<0.05或P<0.01),管理组优于对照组;管理组在干预第24周末临床痊愈率显著高于对照组(P<0.05)。结论中医特色疾病管理模式近期疗效与常规诊疗模式相似,远期疗效优于常规诊疗模式。Objective Applying the disease management theory, to explore suitable disease management of traditional Chinese medicine model for depression patients, and observe its role in the therapeutic effects on depression. Methods The patients visiting depression special clinic of acupuncture and moxibustion department in Beijing TCM Hospital, Capital Medical University, from May 2010 to August 2010 were incorporated as the observation object, and were assigned into the management group and control group. The management group accepted the disease management of traditional Chinese medicine model, including antidepressant medicine treatment, education of traditional Chinese medicine model about depression, regular assessment and foUow-up. Conventional treatment model and treatments were used for the control group. The intervention of both groups lasted for 24 weeks. The changes in measuring indicators including HAMD and CGI were observed before and at the end of week 4, 8, 12, 16, 20, 24 of intervention. Results HAMD index showed significant difference at the end of week 12, 16, 20 and 24 of intervention, the management group was superior to the control group （P〈0.05 or P〈0.01）. CGI index showed significant difference at the end of week 20 and 24 of intervention, the management group was superior to the control group （P〈0.05 or P〈0.01）. Besides, at the end of week 24, the cure rate of the management group was higher than the control group （P〈0.05）. Conclusion The disease management of TCM model had the same effect in short-term effect as the conventional treatment model, while in long-term effect, the former is superior to the latter.

关 键 词：中医特色疾病管理 抑郁症 疗效 

分 类 号：R277.794[医药卫生—中医学]