3种抗风湿中成药乌头碱限量检查  

Limit Test of Aconitine in Three Anti-rheumatic Chinese Traditional Patent Medicines

作　　者：赫清雪[1,2] 王爱武[1] 王楠楠[1,2] 

机构地区：[1]山东大学附属省立医院,山东济南250021 [2]山东中医药大学,山东济南250355

出　　处：《中国中医药信息杂志》2012年第9期59-60,共2页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的建立虎力散胶囊、腰息痛胶囊及盘龙七片的乌头碱限量检查方法。方法采用薄层色谱法,分别考察几种展开剂和显色条件,对3种中成药中乌头碱限量进行检查。结果以环己烷-乙酸乙酯-二乙胺(10∶7∶1)为展开剂,喷以稀碘化铋钾试液然后碘蒸汽熏为最佳,斑点清晰杂质干扰小,分离度好。3种中成药的各3个批次限量检查均符合要求。结论本方法简便、快速,可为这3种中成药的质量控制提供参考。Objective To establish the method of limit test of aconitine in Hulisan capsule, Yaoxitong capsule and Panlongqi tablet. Methods Several developing solvents and coloration conditions were investigated by TLC method. Limit of aconitine in three anti-rheumatic Chinese traditional patent medicines was examined, respectively. Results Cyclohexane-ethyl acetate-diethylamine （10 ： 7 ： 1） was used as developing solvent. TLC was sprayed by potassium heptaiodobismuthate solution, and then fumigated by iodine vapor. The result showed clear spots and well separation. Limit test results of three Chinese traditional patent medicines for three batches were met the requirements. Conclusion This method is simple and fast to control the quality of these three Chinese traditional patent medicines.

关 键 词：虎力散胶囊 腰息痛胶囊 盘龙七片 薄层色谱法 乌头碱限量 

分 类 号：R284.1[医药卫生—中药学]