阿奇霉素对小儿支气管哮喘的影响  

Anti-inflammatory effects of Azithromycin on Asthmatic Children

作　　者：杨希晨[1] 潘伟[1] 万俊[1] 刘桂华[1] 季伟[2] 

机构地区：[1]东南大学医学院附属江阴市人民医院儿科,江苏江阴214400 [2]苏州大学附属儿童医院呼吸科,江苏苏州215003

出　　处：《临床肺科杂志》2012年第10期1770-1771,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨阿奇霉素在小儿支气管哮喘中的作用。方法我科2011年01月至2012年02月期间经过门诊或住院初次诊治的支气管哮喘儿童,根据是否同时使用阿奇霉素治疗分为治疗组和对照组,检测患儿治疗前后肺功能指标。结果治疗组使用阿奇霉素的哮喘患儿,其大小气道指标均得到提高,并且小气道参数提高情况要远胜于对照组,甚至有部分患儿接近正常。结论阿奇霉素能改善支气管哮喘患儿的肺功能,尤其是小气道功能。Objective To explore the anti-inflammatory effects of Azithromycin on asthmatic children. Methods Asthmatic children treated for the first time were divided into treatment group and control group according to whether or not using Azithromycin. The indicators of lung function were detected. Results There were different degree decrease in major and minor airway function in both group. But in Asthma group, the minor airway function improved more significantly. Conclusion Azithromycin has the anti - inflamma- tory effects on the children with asthma.

关 键 词：阿奇霉素 支气管哮喘 儿童 

分 类 号：R725.6[医药卫生—儿科]