Synthesis and Crystal Structure of (E)-4-(3-oxo-3-((4-(N-(pyrimidin-2-yl)-sulfamoyl)phenyl)amino)prop-1-en-1-yl)-1,2-phenylene diacetate Dimethanol  

作　　者：王黎 蒙法艳 彭福长 邓江 林翠梧 

机构地区：[1]College of Chemistry and Chemical Engineering,Guangxi University

出　　处：《Chinese Journal of Structural Chemistry》2012年第10期1497-1500,共4页结构化学（英文）

基　　金：supported by the National Natural Science Foundation of China(20962002,20662001)

摘　　要：The title compound, （E）-4-（3-oxo-3-（（4-（N-（pyrimidin-2-yl）sulfamoyl）-phenyl）ami- no）prop- 1-en- 1-yl）- 1,2-phenylene diacetate dimethanol, was synthesized by the reaction of caffeic acid with sulfadiazine and characterized by FT-IR, 1H-NMR spectroscopy, ESI-MS and X-ray single-crystal diffraction. It crystallizes in triclinic, space group P1 with a = 10.302（7）, b = 11.621（8）, c = 12.107（8）A, a = 100.904（9）, β = 102.624（8）, y = 95.501（9）°, V= 1374.5（15）A3, Z= 2, F（000） = 588, D,= 1.354 Mg/m3, Mr = 560.57,μ= 0.176 mm-1, 2 = 0.71073 A, the final R = 0.0666 and wR = 0.1950 for 4774 observed reflections with I 〉 2σ（I）.The title compound, （E）-4-（3-oxo-3-（（4-（N-（pyrimidin-2-yl）sulfamoyl）-phenyl）ami- no）prop- 1-en- 1-yl）- 1,2-phenylene diacetate dimethanol, was synthesized by the reaction of caffeic acid with sulfadiazine and characterized by FT-IR, 1H-NMR spectroscopy, ESI-MS and X-ray single-crystal diffraction. It crystallizes in triclinic, space group P1 with a = 10.302（7）, b = 11.621（8）, c = 12.107（8）A, a = 100.904（9）, β = 102.624（8）, y = 95.501（9）°, V= 1374.5（15）A3, Z= 2, F（000） = 588, D,= 1.354 Mg/m3, Mr = 560.57,μ= 0.176 mm-1, 2 = 0.71073 A, the final R = 0.0666 and wR = 0.1950 for 4774 observed reflections with I 〉 2σ（I）.

关 键 词：caffeic acid SULFADIAZINE synthesis crystal structure 

分 类 号：O621.2[理学—有机化学]