咪唑斯汀与氯雷他定抗炎作用对比  

Comparative Study About Anti Inflammatory Effect between Mizolastine and Loratadine

作　　者：刘可[1] 高以红[1] 李超[1] 

机构地区：[1]江苏省江阴市中医院皮肤科,江苏江阴214400

出　　处：《中国医药指南》2012年第26期35-36,共2页Guide of China Medicine

摘　　要：目的探讨咪唑斯汀与氯雷他定在治疗皮肤疾病时抗炎作用的比较。方法选取炎性反应明显的志愿参加此研究的78名患者,给予咪唑斯汀或者氯雷他定服用,分别于服用药物后1d,3d,7d记录炎性反应最明显的一块红斑面积和风团面积。咪唑斯汀为试验验组,氯雷他定为对照组。结果服用药物1d后,服用咪唑斯汀组红斑面积及风团面积变化显著优于氯雷他定组(P<0.05);服用药物3d,7d后,服用咪唑斯汀组风团面积减退情况显著优于氯雷他定组(P<0.05)。结论咪唑斯汀能明显治疗皮肤炎性反应。Objective To study the different anti inflammatory effect on human skin disease between miolastine and loratadine.Methods Select 78 volunteers who is showing inflammatory reaction obviously.Give them taking mizolastine or loratadine.Record the area of erythema and wheal which is showing obvious anti inflammatory after taking pills 1d,3d,7d..The voluntees who taked mizolastine is test group.The volunteers who taked loratadine is control group.Results After taking pills 1d,the mizolastine group show better effect of reducing the area of wheal than the loratadine group（P0.05）;After taking pills 3d,7d,the mizolastine group show better effect of reducing the area of erythema and wheal than loratadine（P0.05）.Conclusion Mizolastine had a stong inhibitory effect on anti inflammatory of human skin.

关 键 词：抗炎作用 咪唑斯汀 氯雷他定 

分 类 号：R978.1[医药卫生—药品]