逐瘀还五解毒颗粒治疗冠心病心绞痛临床研究  

Clinical Research of Zhuyu Huanwu Jiedu Granule in Treating Coronary Angina Pectoris

作　　者：李凯文 史佃磊 王凤红 唐海莲 

机构地区：[1]昌乐县中医院,山东昌乐262400 [2]昌乐县五图医院,山东昌乐262406

出　　处：《中医学报》2012年第10期1327-1328,共2页Acta Chinese Medicine

摘　　要：目的:探讨逐瘀还五解毒颗粒对冠心病心绞痛的症状及心电图变化的影响,评估逐瘀还五解毒颗粒治疗冠心病心绞痛的临床疗效。方法:将94例冠心病心绞痛患者随机分为两组,对照组给予基础西药治疗,治疗组在对照组治疗基础上加用逐瘀还五解毒颗粒(方药组成:桃仁12 g,红花9 g,当归9 g,生地黄9 g,川芎4.5 g,赤芍6 g,牛膝9 g,桔梗4.5 g,柴胡3 g,枳壳6 g,甘草6 g,黄芪18 g,地龙9 g,金银花12 g,蒲公英12 g)治疗,2周为1个疗程。结果:治疗组患者的症状及心电图的改善明显优于对照组。结论:逐瘀还五解毒颗粒治疗冠心病心绞痛疗效满意。Objective：To explore the influence of Zhuyu Huanwu Jiedu granule on coronary angina pectoris on clinical symptoms and electrocardiogram changes and evaluate the clinical effects of zhuyu huanwu jiedu granule in treating coronary angina pectoris.Methods：94 cases of coronary angina pectoris were randomly divided into two groups.The control group was treated by basic western medicine.The treatment group was orally given Zhuyu Huanwu Jiedu granule（composition：peach kernel 12 g,safflower 9 g,Angelica 9 g,dried rehmannia root 9 g,hemlock parsley 4.5 g,red peony root 6 g,Achyranthes bidentata 9 g,Platycodon grandiflorum 4.5 g,Chinese thorowax 3 g,fructus 6 g,licorice root 6 g,Astragalus membranaceus 18 g,Earthworm 9 g,honeysuckle 12 g,dandelion12 g） based on the control group.2 weeks were one treatment course for both groups.Results：Patients′ clinical symptoms and the improvement of electrocardiogram in the treatment group were obviously superior to the control group.Conclusion：Zhuyu Huanwu Jiedu granule has a satisfactory therapeutic effect in treating coronary angina pectoris.

关 键 词：冠心病心绞痛 逐瘀还五解毒颗粒 硝酸酯类 β受体阻滞剂 钙拮抗剂 抗血小板及调血脂药物 

分 类 号：R259.414[医药卫生—中西医结合]