组合化学方法研究对甲苯磺酸乳酸乙酯的合成工艺  

Process Study of Ethyl (p-tosylate) lactate with Combinatorial Strategy

作　　者：李斌[1] 耿丽文[1] 王良清[1] 周宁[1] 

机构地区：[1]沈阳化工研究院,沈阳110021

出　　处：《农药》2000年第6期14-15,共2页Agrochemicals

摘　　要：用平行组合合成方法 ,一次进行 15个反应 ,用气相色谱对反应进行跟踪分析 ,考察了 6种溶剂、5种碱对生产喹禾灵等除草剂的关键中间体对甲苯磺酸乳酸乙酯合成收率的影响 ,发现极性溶剂对反应有利。在工艺研究中应用组合化学方法 ,会节省时间和工作。reactions were run at the same time with parallel combinatorial strategy for the process study of ethyl (p-tosylate) lactate which is a key intermediate in the manufacturing aryloxyphenoxy herbicides such as quizalofop-ethyl. The preliminary results showed that the polar solvents are better to the reaction. It seems that the combinatorial strategy is a useful tool for the process study of some chemicals.

关 键 词：组合化学 工艺研究 对甲苯磺酸乳酸乙酯 除草剂 

分 类 号：TQ45[化学工程—农药化工]