病理性瘢痕形成中VEGF表达及调控的研究进展  

Development Study on VEGF Expression and Regulation of Pathological Scar Formation

作　　者：武元元[1] 张选奋[2] 

机构地区：[1]兰州大学第二临床医学院,甘肃兰州730030 [2]兰州大学第二医院整形外科,甘肃兰州730030

出　　处：《现代生物医学进展》2012年第26期5178-5181,共4页Progress in Modern Biomedicine

基　　金：国家自然科学基金资助项目(30672185)

摘　　要：病理性瘢痕一直是整形外科乃至整个外科界研究的热点,由于其发病机制十分复杂,迄今尚无明确的病因学诊断和有效的治疗方法。VEGF作为目前活性最强的血管生长因子,与病理性瘢痕的发生、发展关系密切。研究病理性瘢痕形成过程中VEGF的表达及调控机制,有助于阐明病理性瘢痕的发病机制,为预防和治疗病理性瘢痕提供依据。Pathological scar is still the research focus in the plastic surgery and even all surgical field.Due to its very complex pathogenesis, there is no clear etiology diagnosis and effective treatment at present. VEGF as the most active vascular growth factor has close relationship with the occurrence and development of pathological scars. To study the VEGF expression and regulation mechanism in the course of pathological scar formation will not only be favorable to elucidate its pathogenesis but also provide theoretical foundation for its prevention and treatment.

关 键 词：病理性瘢痕 VEGF 表达 调控 

分 类 号：R619.6[医药卫生—外科学]