急性冠脉综合征患者血浆超敏C反应蛋白检测的临床价值  

Clinical value of acute coronary syndrome patients with high sensitivity C reactive protein

作　　者：尹宏磊[1] 户富栋[1] 王亚坤[1] 

机构地区：[1]新乡医学院一附院心内一科,河南卫辉453100

出　　处：《成都医学院学报》2012年第02Z期317-318,共2页Journal of Chengdu Medical College

摘　　要：目的：探讨超敏c-反应蛋白的检测在诊断急性冠脉综合征（ACS）患者的临床应用价值。方法：回顾分析新乡医学院一附院心内一科2009年8月至2010年12月收治的105例急性冠脉综合征患者的临床资料。另外，选取选取98例在我院健康查体中心进行体检的身体健康人员，男64例，女34例。平均年龄59．3±7．6岁，年龄范围在40-80岁左右。所有患者均于入院后第二天清晨及治愈出院前分别空腹采集静脉血4ml。凝固后3000r／min，离心10min，分离血清于-70℃低温冰箱冻存待测。对照组采集晨起空腹静脉血4ml，按照同样方法进行分离，冻存待测。所有标本均无溶血。结果：对照组98例健康体检者，经检测hs—Clip值为（2．34±0．67）mg／L，急性心肌梗死组68例患者，hs—cRP值为（12．68±6．20）mL，与对照组比较，差异有极显著性，P〈0．001；稳定性心绞痛组23例患者，hs—CRP值为（8．54±3．62）mg／L，与对照组比较，差异有显著性，P〈0．01；不稳定性心绞痛14例患者，hs—cRP值为（3．58±2．46）mg／L。与对照组比较，差异有显著性，P〈0．05。结论：超敏C-反应蛋白（hs—CRP）的检测在急性冠脉综合征患者的诊断中有非常重要的临床价值。Objective： To investigate the detection of high sensitivity c -reactive protein in the diagnosis of acute coronary syndrome （ACS） in patients with clinical value. Methods ： A retrospective analysis of clinical data of a Division of the heart of First Affiliated Hospital of Xinxiang Medical College from August 2009 to December 20 Ill were 105 cases of patients with acute coronary syndrome. Also, select 98 cases a medical examination, the health personnel in the hospital health examination center, 64 males, 34 females, mean age 59.3 ± 7.6 years old, the age range of 40 to 80 years. All patients were admitted to hospital after the next morning and cure, respectively, collected fasting prior to discharge blood 4ml solidified 3000 r / min, centrifugal lOmin, separated serum frozen at - 70℃ low temperature refrigerator test. The control group collected early morning fasting blood 4ml, follow the same method were separated, frozen under test. All specimens had no hemolysis. Results： The control group of 98 healthy subjects, the detection of hs - CRP values （2.34 ±0. 67 ） mg / L, 68 cases of acute myocardial infarction patients, hs - CRP value （ 12.68 ± 6.20） m L, compared with the control group, the difference was very significant （ P 〈 0.001 ） ; unstable angina group of 23 patients, hs - CRP values （8.54± 3.62 ） mg / L, compared with the control group, the difference was significant , P 〈 0. 01 ; unstable angina in 14 patients, hs - CRP value （3.58 ± 2.46） mg / L, compared with the control group, the difference was significant （ P 〈 0.05 ）. Conclusion ： the detection of ultra - sensitivity C - reactive protein （ hs - CRP）, a very important clinical value in the diagnosis of acute corenary syndrome.

关 键 词：急性冠脉综合征 超敏C-反应蛋白 检测 

分 类 号：R457.14[医药卫生—治疗学]