醛固酮和脑血管病关系的研究进展  

Study Progress of the Relations between Aldosterone and Cerebrovascular Diseases

作　　者：赵素芳[1] 姚晓光[2] 李南方[2] 

机构地区：[1]新疆石河子大学医学院,新疆石河子832000 [2]新疆维吾尔自治区人民医院高血压中心,新疆高血压研究所,乌鲁木齐830001

出　　处：《医学综述》2012年第19期3148-3150,共3页Medical Recapitulate

基　　金：新疆维吾尔自治区重点实验室开放课题(XJYS0906-2011-04)

摘　　要：脑血管疾病是造成人类死亡的三大疾病之一,也是高血压患者的主要致死原因。在幸存者中绝大多数留有后遗症状,部分患者丧失劳动和生活能力,给社会和家庭带来沉重的负担。多项研究显示,原发性醛固酮增多症较原发性高血压患者而言,靶器官损害出现更早、程度更重,在高血压人群中筛查原发性醛固酮增多症,尽早予醛固酮受体拮抗剂,或许可以为脑血管病的预防、治疗提供理论依据,并可降低致死、致残率。The cerebrovaseular disease is one of the three diseases resulting in death and the main cause of death for hypertension patients. The majority of survivors have different grades of disability bringing bur- dens to the family and society. Many studies indicate that primary aldosteronism result in earlier and heavier target organ damage than essential hypertension. Screening of primary aldosteronism from hypertension popu- lation and the early use of aldosterone receptors antagonist may provide evidence for the prevention and treat- ment of the eerebrovascular diseases and reduce the fatality and disability rate.

关 键 词：脑血管病 高血压 醛固酮 醛固酮受体拮抗剂 

分 类 号：R544.1[医药卫生—心血管疾病]