高浓度对比剂在冠状动脉多排螺旋CT的应用  

Usage of high concentrative contrast media in coronary CTA

作　　者：王永梅[1,2] 李宇[1,2] 张兆琪[1,2] 范占明[1,2] 吕飙[1,2] 

机构地区：[1]首都医科大学附属北京安贞医院 [2]北京市心肺血管疾病研究所影像科,北京100029

出　　处：《心肺血管病杂志》2012年第5期596-599,共4页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:探讨高浓度对比剂在冠状动脉多排螺旋CT(multidetector-row computed tomographicangiography,MDCTA)的应用效果。方法:冠心病筛查者60例随机分为两组,每组30例;分别采用400mg I/mL和350 mg I/mL浓度的对比剂进行MDCTA检查,在流率为3.7 mL/s和对比剂总量,2组间差异无统计学意义,并计算两组的心功能指标,对冠状动脉主干、主要分支血管近段及主动脉血管强化程度进行比较,对重建血管清晰度进行评价。结果:两组心功能指标差异无统计学意义,400 mg I/mL组血管强化程度优于350 mg I/mL组(P<0.05),两组差异具有统计学意义,重建血管清晰度各组间差异无统计学意义。结论:在较低流速下,高浓度对比剂400 mgI/mL浓度较350 mgI/mL浓度对比剂图像质量好,冠状动脉及主动脉血管强化程度高,重建血管清晰度无差异。Objective：To investigate the effect of high concentration contrast media in the coronary ar- tery angiography by using multi-detector row computed tomography （MDCT）. Methods： 60 continuously pa- tients who underwent coronary artery angiography with MDCT were divided into two groups. 350 mg/mL and 400 mg/mL were used in two groups, respectively. The contrast medium injection rate （3.7 mL/s） had no sig- nificance between the two groups. The degree of enhancement of coronary artery and the definition of the recon- structed artery were evaluated. Results： The degree of enhancement of coronary artery in group 400 mgI/mL were higher significantly than that of group 350 mg I/mL. The heart function and the qualities of the coronary arteries had no significance between the two groups. Conclusion： Compared with 350 mg I/mL, high concen- trative contrast media can elevate the degree of enhancement of coronary arteries with low injection rate.

关 键 词：冠状动脉 高浓度对比剂 计算机体层摄影 

分 类 号：R541.4[医药卫生—心血管疾病]