孕妇血清中HBVDNA含量及HBVM与HBV宫内感染关系的研究  

作　　者：韩文导[1] 

机构地区：[1]梅州市人民医院检验科,514200

出　　处：《大众健康（理论版）》2012年第8期21-22,共2页

摘　　要：目的：研究孕妇血清中HBVDNA含量和HBV血清标志物与HBV宫内感染的相关性。方法：采用ELISA法和FQ—PCR法检测169例HBsAg阳性孕妇外周静脉血及其新生儿静脉血五项HBV血清标志物和HBVDNA含量。结果：169例HBsAg阳性孕妇分娩的新生儿HBV宫内感染率为819％；其中HBeAg阳性孕妇的新生儿宫内感染率为2812％，HBeAg阴性的孕妇的新生儿宫内感染率为3．65％，两者差异具体统计学意义（P〈0．01）。结论：HBeAg和HBVDNA均为发生HBV宫内感染的重要危险因素．孕妇HBVDNA含量≥10。时，易发生HBV宫内感染，HBVDNA的含量与宫内感染的发生成正相关。Objective： The pregnant women in serum HBVDNA content and HBV serum markers and HBV infection in the correlation.Method=Using ELISA method and FQ - PCR method to detect 169 cases of HBsAg positive women peripheral venous blood and neonatal venous blood five HBV serum markers and HBVDNA content.Result. 169 cases of HBsAg positive women delivery newborns in HBV infection rate was 8.19%; H BeAg positive of pregnant women in newborn infection rate was 28.12% BeAg negative pregnant women in newborn infection rate was 3.65% F difference in specific statistical significance （P 〈 0.01）.Conclusion. HBeAg and HBVDNA are happened in HBV infection of the important risk factors. Pregnant women HBVDNA content was 103, easy to occur in HBV infection, the content of HBVDNA and intrauterine infection into positive correlation.

关 键 词：乙型肝炎病毒 宫内感染 DNA 

分 类 号：R512.62[医药卫生—内科学]