非霍奇金淋巴瘤与乙型肝炎病毒感染相关性的研究进展  

Research progress on the relationship between non-Hodgkin ＂s lymphoma and hepatitis B virus infection

作　　者：彭芳(综述)[1] 白鸥(审校)[2] 王银萍(审校)[1] 

机构地区：[1]吉林大学白求恩第一医院病理科,长春130021 [2]吉林大学白求恩第一医院血液肿瘤科,长春130021

出　　处：《白血病．淋巴瘤》2012年第9期561-563,共3页Journal of Leukemia & Lymphoma

基　　金：吉林省卫生厅科技计划（20112038）

摘　　要：乙型肝炎病毒（HBV）感染呈全球性分布，并有嗜肝细胞和嗜淋巴细胞特性；全世界非霍奇金淋巴瘤（NHL）总体发病率和死亡率逐年增高。研究表明NHL患者HBV标志物阳性率显著高于健康人群，同时高于除原发性肝癌以外的其他实体肿瘤患者，如肺癌、胃肠道肿瘤及乳腺癌等；乙型肝炎患者患NHL的风险增加。但是两者之间的确切关系并不明确，文章就NHL与HBV感染相关性研究进行综述。Hepatitis B virus （HBV） infection is global distribution, and HBV has hepatotropic and lymphotropie characteristics. The incidence and mortality of non-Hodgkin＂ s lymphoma （NHL） arc steadily increasing in the world. The survey research shows that the prevalence of positivity for HBV surface antigen in patients with NHL is significantly higher than healthy people, at the same time, higher than patients with solid tumors, in addition to primary liver cancer, such as lung cancer, gastrointestinal tumors and breast cancer, etc. Chronic HBV infection individuals increase risk of development of NHL. But the exact relationship between them is not clear, it will be reviewed in this paper.

关 键 词：淋巴瘤 非霍奇金 肝炎病毒 乙型 感染 

分 类 号：R512.62[医药卫生—内科学]