心理行为疗法和西地那非治疗前列腺近距离放疗后勃起功能障碍的治疗体会  

The therapeutic experience of psycho-behavior therapy and sildenafil on erectile dysfunction after prostate brachytherapy

作　　者：范钰[1] 袁光亚[1] 辛宇鹏[1] 邵红刚[1] 王耀东[1] 

机构地区：[1]绵阳市中心医院泌尿外科,四川绵阳621000

出　　处：《四川医学》2012年第9期1515-1517,共3页Sichuan Medical Journal

基　　金：四川省卫生厅科研课题基金资助(编号:070202)

摘　　要：目的探讨采用心理行为疗法和西地那非治疗前列腺近距离放疗(PB)后患者勃起功能障碍(ED)的疗效。方法研究总共纳入22例单一的125I粒子置入前列腺近距离放疗后ED的患者,主要采用心理行为疗法进行治疗,在治疗开始时和以后每3个月完成国际勃起功能评分-5(IIEF-5)问卷调查,共随访12个月。在第3个月及后续随访期间时,如IIEF-5分数≤17分,则建议患者服用西地那非片。结果 22例患者的治愈率为86.4%,其中有15例患者仅采用心理行为疗法进行治疗,治愈率为93.3%;7例患者加用了西地那非片治疗(均在第3个月时),治愈率为71.4%。治疗开始时、第3个月和第12个月患者平均IIEF-5分数分别为:13.3、19.2和22.9(P<0.05)。结论心理行为疗法和西地那非治疗PB后ED能取得显著的疗效。Objective To discuss our therapeutic effect of psycho-behavior therapy and sildenafil on erectile dysfunction （ED） after prostate brachytherapy （PB）. Methods A total 22 patients of ED who were treated with single 125I-seed implantation were enrolled. Psycho-behavior treatment was prescribed alone chiefly. Each patient was evaluated by International Index of Erec- tile Function-5 （IIEF-5） at the baseline and every 3 months in 12 months. If IIEF-5 scores ≤17 at first 3 months or later period, sildenafil would be advised. Results 22 patients＇ cure rate was achieved 86. 4%, of which 15 patients with 93. 3% cure rate were treated only psycho-behavior therapy; 7 patients with 71.4% cure rate had prescribed sildenafil at first 3 months. The IIEF-5 scores were ： 13. 3, 19.2 and 22.9 （P 〈 0.05） at the baseline, sixth month and twelfth month. Conclusion Psycho-behavior thera- py and sildenafil could aehieve a significant therapeutic effect on ED after PB.

关 键 词：前列腺近距离放疗 勃起功能障碍 心理行为疗法 西地那非 

分 类 号：R698.1[医药卫生—泌尿科学]