老年慢性肾脏病患者体液分布变化与高血压的关系  

Relation between body fluid distribution and blood pressure in elderly chronic kidney disease patients

作　　者：刘胜[1] 程庆砾[1] 张晓英[1] 杨光[1] 王晓华[1] 

机构地区：[1]解放军总医院南楼肾科,北京100853

出　　处：《中华老年心脑血管病杂志》2012年第10期1051-1053,共3页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的研究老年慢性肾脏病(CKD)患者体内液体分布情况及其与血压的关系。方法选择2～3期老年CKD患者66例(CKD组),同期在老年病房住院体检或治疗的老年非CKD患者68例(对照组)。使用生物电阻抗方法评估受试者体液组成,并对相关数据进行比较分析。结果 CKD组高血压患病率明显高于对照组(65.2%vs41.2%,P<0.05);3期CKD患者高血压患病率明显高于2期CKD患者(80.0%vs 48.4%,P<0.05);CKD组体液总量及细胞外液成分明显高于对照组,差异有统计学意义(P<0.05);3期CKD患者体液总量及细胞外液容量明显高于2期CKD患者,差异有统计学意义(P<0.05)。结论老年CKD患者即使没有临床显性水肿,其体液成分已经发生变化;2～3期老年CKD患者高血压可能与体液总量和细胞外液增高有关。Objective To study the relation between body fluid distribution and blood pressure in elderly chronic kidney disease （CKD） patients. Methods Sixty-six elderly 2- 3 stage CKD pa- tients served as a CKD group and 68 non-CKD patients served as a control group in this study. Compositions of their body fluid were assessed by bioimpedance analysis（BIA） and the relative data were analyzed. Results The incidence of hypertension was significantly higher in CKD group than in control group（65.2% vs 41.2%,P〈0.05） and in 3-stage CKD pathients than in 2 stage CKD patients（80.0% vs 48.4%,P〈0.05）. The total body fluid volume and extracellular fluid volume were significantly larger in CKD group than in control group（P〈0.05） and in 3-stage CKD patients than in 2-stage CKD patients（P〈0.05）. Conclusion Compositions of body fluid have changed in elderly CKD patients even though they have no significant edema in clinic. Hyper- tension in elderly 2--3 stage CKD patients may be relatd with the elevated total body fluid and extraeellular fuild volume.

关 键 词：高血压 肾疾病 体液分布 电阻抗 细胞外液 氯化钠 膳食 

分 类 号：R692[医药卫生—泌尿科学] R544.1[医药卫生—外科学]