多孔β型钛合金及其微弧氧化涂层的体内植入研究  

Implantation Study of Porous β Titanium Alloy and Its MAO Coatings

作　　者：井文森[1] 韩建业[2] 张明华[1] 蔡和平[3] 于振涛[2] 高铜拴[1] 

机构地区：[1]第四军医大学唐都医院,陕西西安710038 [2]西北有色金属研究院,陕西西安710016 [3]西安交通大学,陕西西安710048

出　　处：《稀有金属材料与工程》2012年第9期1657-1660,共4页Rare Metal Materials and Engineering

基　　金：国家自然科学基金(面上项目)(30870611)

摘　　要：采用球形TLM:Ti-Zr-Sn-Mo-Nb粉末松装烧结在中心件表面制备多孔件,利用微弧氧化技术在多孔件表面进行改性,并制备复合有BMP的涂层。对多孔件和微弧氧化件的表面形貌、结构和成分进行分析;通过动物体内植入实验评价β型钛合金多孔材料生物涂层周围骨组织界面的新骨形成情况。结果表明:3种表面涂层均具有良好的生物相容性,但PCI/HA和PCI/HA2种复合涂层组较PCI组有明显的骨诱导活性,具有良好的临床应用前景。Porous pieces were prepared with the alloy powder （TLM：Ti-Zr-Sn-Mo-Nb） and centre stick by means of sintering. The surface of porous pieces was modified with MAO. Another composite coating with BMP was prepared. The surface morphology, microstructure and composition of the three kinds of test pieces were analyzed. The new bone tissue around the coatings of these test pieces were evaluated according to animal implantation experiment. The results show that all of the three surface coatings have good biocompatibility. The PCI/HA group and PCI/HA/BMP group have excellent osteoconductivity and a good prospect of clinical application

关 键 词：Β型钛合金 多孔 涂层 微弧氧化 骨形态发生蛋白 

分 类 号：R687.4[医药卫生—骨科学]