柴胡汤剂中次生柴胡皂苷结构研究  

Structure of secondary saikosaponins in saiko decoction

作　　者：李军[1] 姜华[1] 张延萍[1] 张倩[1] 徐幽[1] 

机构地区：[1]河南科技大学化工与制药学院,河南洛阳471003

出　　处：《中国中药杂志》2012年第20期3078-3082,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(81001615)

摘　　要：目的:研究柴胡煎煮过程中新生成的柴胡次生皂苷的结构。方法:采用各种分离技术和光谱技术对柴胡煎液中柴胡皂苷的结构进行分离和结构鉴定。采用HPLC对所分离得到的柴胡皂苷进行指认。结果:从柴胡汤剂中分离得到11个柴胡皂苷,对柴胡煎煮过程中新生成的7个成分中的4个进行了指认。结论:为从次生柴胡皂苷的角度完善柴胡的认识奠定基础。Objective： To study the structures of secondary saikosaponins in saiko decoction, Method： The structures of sai- kosaponins were separated from saiko decoction and identified by various separation and spectral techniques. HPLC method was adopted for identifying all of separated saikosaponins. Result： Eleven saikosaponins were separated from saiko decoction. Four of the seven new constitutes contained in saiko decoction were identified. Conclusion： This study lays a foundation for improving the identification of secondary saikosaponins.

关 键 词：柴胡 汤剂 次生柴胡皂苷 

分 类 号：R284[医药卫生—中药学]