肿瘤微波热疗三维温度场热域控制及红外热成像  

Thermal Volume Control of 3D Temperature Field and Infrared Thermography in Tumor Microwave Hyperthermia

作　　者：马国军[1,2] 江国泰[1] 陈志宏[1] 

机构地区：[1]同济大学生命科学与技术学院,上海200092 [2]江苏科技大学电子信息学院,江苏镇江212003

出　　处：《北京工业大学学报》2012年第10期1582-1587,共6页Journal of Beijing University of Technology

基　　金：国家自然科学基金资助项目(50977064)

摘　　要：研究了肿瘤热疗过程中正弦调制信号控制微波辐照时的均匀仿真模型内部三维温度场分布以及热域体积.为使肿瘤区域内产生有效的热效应,提出正弦信号调制微波输出,对三维分层仿真模型中各层的温度进行红外热成像分析,然后对三维温度场进行光线投射重建,测量三维有效热域的相对体积,分析讨论正弦调制微波功率和周期对生物组织加热区域内温度分布与三维热域相对体积的影响.结果表明,正弦调制信号控制微波加热可有效控制生物组织内部的温度分布;采用提高正弦调制微波功率、在一定范围内改变调制微波的周期的方式来提高生物组织加热区域内的热效应和热域体积,可为肿瘤微波热疗三维温度场热域控制、观察与测量提供初步依据。Inner 3D temperature field distribution of homogeneous phantom and thermal volume are studied when microwave radiation is modulated by sine signal during tumor hyperthermia.To get heating effect in tumor volume,sine signal modulated microwave is proposed to control temperature field distribution.Infrared thermography was applied to image temperature of 3D multi-layered homogeneous phantom,3D temperature field was then reconstructed by ray casting,and 3D relative thermal volume was measured.The heating effects of power and period of sine modulated microwave radiated phantom were analyzed and discussed.Results show that sine modulated microwave may effectively control inner temperature distribution of phantom.The raised power or changed period in certain range make distinct heating effect and thermal volume in phantom.This provides preliminary basis for thermal volume control,survey and measurement of 3D temperature field in tumor hyperthermia.

关 键 词：微波热疗 三维温度场 正弦调制微波 红外热成像 

分 类 号：TN219[电子电信—物理电子学]