256例自诉不明原因感染患者的临床特征分析  

Clinical features of 256 readme patients infected with unknown pathogens

作　　者：谢栩硕[1] 曾文铤[1] 梁建新[1] 梁增伟[1] 黄晓菡[1] 

机构地区：[1]广州医学院第一附属医院感染内科,广东广州510120

出　　处：《中华医院感染学杂志》2012年第20期4525-4527,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析有关临床资料,探索自诉不明原因感染患者的临床特征,为其诊治提供参考依据。方法收集在医院门诊及住院的自述不明原因感染患者256例,对其流行病学、临床症状及体征、辅助检查、实验室病原体检测以及心理测试量表等各项资料进行综合分析,并探讨与人疱疹病毒的相关性。结果 256例患者,男性占86.72%,女性占13.28%;67.9%患者有高危性行为史、临床主诉多、并反复出现,仅37.1%患者有阳性体征,重要脏器功能无异常;仅4.3%的患者出现CD4+减少;全部患者HIV检测阴性;73.0%患者在多种标本中检出人疱疹病毒阳性;12例接受心理测试发现异常有9例。结论患者无重要器官病变,可排除HIV感染,是否与人疱疹病毒感染相关,有待进一步研究。OBJECTIVE To analyze the clinical data,and explore the clinical features of the patients infected with readme unknown pathogens so as to provide evidence for the clinical diagnosis and treatment.METHODS A total of 256 patients infected with unknown pathogens were collected,the epidemiology,clinical symptoms and signs,laboratory examinations,laboratory pathogen detection,and the psychological test scale were comprehensively analyzed,the correlation with human herpes virus was evaluated.RESULTS Of 256 patients,the male patients accounted for 86.72%,13.28% of the female patients;67.9% of patients were with high-risk sexual behavior.Only 37.1% patients were with positive signs,and there were no abnormal function of important organs,only 4.3% of the patients were with emergence of CD4＋ reducing;all the patients were detected with HIV negative;73.0% of patients were detected with human herpes virus positive from various specimens;there were 9 of 12 cases undergoing psychological test which were abnormal.CONCLUSION The patients without the major organ lesions involved can rule out the possibility of HIV infection,it needs to be further studied whether they are related to the human herpes virus infection.

关 键 词：自诉不明原因感染 患者 临床特征 人疱疹病毒 感染 

分 类 号：R181.32[医药卫生—流行病学]