急性肾上腺皮质危象20例临床分析  

Clinical analysis of acute addisonian crisis in 20 cases

作　　者：包文苟 

机构地区：[1]湖南省茶陵县人民医院,湖南茶陵412400

出　　处：《中国当代医药》2012年第28期27-28,共2页China Modern Medicine

摘　　要：目的探讨急性肾上腺皮质危象的临床特征及诊治特点。方法回顾性分析20例急性肾上腺皮质危象患者的临床资料。结果 (1)主要临床表现为高热、胃肠道症状、极度衰弱状(疲乏无力、萎靡嗜睡、精神不振)及休克等。(2)实验室检查结果主要表现为白细胞总数增高,中性粒核细胞增多、低钠血症、低血糖症及血皮质醇水平降低。(3)转归:经系统治疗后,好转19例(95.00%),死亡1例(5.00%),死亡原因为感染性休克,因抢救无效而死亡。结论急性肾上腺皮质危象临床表现多样,须仔细询问病史并进行全面细致的检查,以及时明确诊断并尽快大量使用糖皮质激素,以免耽误抢救时机。Objective To investigate the feature of clinical symptom and treatment for acute addisonian crisis. Methods Clinical data of twenty cases with acute addisonian crisis were measured by retrospective analyzed. Results （1）The major clinical manifestations were hyperpyrexia, gastrointestinal symptom （GIS） together with extreme weakness, fatigability, cachexia and shock. （2）The main results of laboratory examinations were that hemameba and polymorphonuclear neutrophils increased, hyponatremia, hypoglycemia, level of serum cortisol decreased. （3）Sequelae： after the systemic treatment, 19 cases were took turn for the better （95.00%）. While 1 case （5%） rescue invalid died due to the infectious shock. Conclu- sion The clinical manifestations are complex and various of acute Addisonian crisis. Before the treatment, it must know the detail medical history and take a complete inspection for patients to get a specific diagnosis and inject glucocorticoid in time to make sure no delay of emergency time.

关 键 词：肾上腺皮质危象 急性 诊断 治疗 

分 类 号：R586[医药卫生—内分泌]