奥司他韦对重症甲型H1N1流感的疗效观察  

Curative effect observation on oseltamivir efficacy in the treatment of severe influenza A(H1N1)

作　　者：兰帝仕[1] 

机构地区：[1]福建省福州儿童医院(福建医科大学教学医院),福建福州350002

出　　处：《中国当代医药》2012年第28期82-83,共2页China Modern Medicine

摘　　要：目的观察奥司他韦对重症甲型H1N1流感的疗效。方法 40例重症甲型H1N1流感患者应用奥司他韦治疗,分别于治疗前及治疗后第1天、第3天观察患儿发热、咳嗽、流涕等流感样症状和肺部啰音。根据患儿临床表现,按显效、有效、进步、无效4个等级进行疗效评定。结果 40例患者中,12例(占30.0%)显效,23例(占57.5%)有效,3例(占7.5%)进步,2例(占5.0%)无效。总有效率为87.5%。结论奥司他韦对甲型H1N1流感有较好的疗效,患者依从性好,未见明显不良反应。感染甲型H1N1流感的人群应及时给予奥司他韦进行抗病毒治疗。Objective To observe the curative effect of oseltamivir in the treatment of severe influenza A （H1N1）. Methods Forty cases of severe influenza A （H1N1） patients were treated with osehamivir, and flu-like symptoms such as fever, cough, runny nose and pulmonary rales were observed before treatment and after one day, three days. According to clinical manifestation of children, the efficacy was assessed on the basis of four levels-markedly effective, effective, progressive, and invalid. Results In 40 cases, 12 cases （accounted for 30.0%） were markedly effective, 23 cases （accounted for 57.5%） were effective, 3 cases （accounted for 7.5%） were progress and 2 cases （accounted for 5.0%） were invalid. The total effecive rate was 87.5%. Conclusion Osehamivir has a good effect in influenza A （HIN1） with good compliance, and no significant adverse reactions is observed. Osehamivir should be timely given in anti-viral therapy of influenza A （H1N1） treatment.

关 键 词：奥司他韦 甲型H1N1流感 疗效观察 抗病毒 

分 类 号：R511.7[医药卫生—内科学]